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NCT05345288 · ClinicalTrials.gov registry record · NA
Effect of Computerized Cognitive Training in Persons With MS
A NA study, sponsored by University of Nebraska.
- Completed
- Registry status
- NA
- Development phase
- 53
- Enrollment target
NCT05345288 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 53 participants.
The verdict
NCT05345288, a NA study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- NA
- Development phase
- 53 participants
- Enrollment target
Study Summary
Multiple sclerosis (MS) affects approximately one million people in the United States and 2.5 million worldwide. Between one million and 1.75 million persons with MS (PwMS) worldwide are estimated to suffer from cognitive impairment. Unfortunately, there is currently no consensus on the best treatment for cognitive impairment in PwMS. The objective for this study is to determine if a computerized cognitive training using the BrainHQ platform can improve cognitive impairment in PwMS. The central hypothesis is that computerized cognitive training will show some improvement in cognitive impairment. The rationale for this study is to treat all aspects of MS, not just the physical symptoms and to help PwMS live their best life. Cognitive impairment is associated with higher rates of depression in PwMS and depression leads to medication non-adherence. This means the cognitive impairment so many PwMS are dealing with must be treated. Finding non-pharmacological interventions to mitigate cognitive declines are essential to ensure that quality of life for PwMS patients matches our ability to treat and mitigate their physical symptoms of MS. To obtain the overall objectives for this study the following specific aim will be pursued: Determine the effectiveness of computerized cognitive training on changes in cognitive impairment for PwMS. This will be accomplished by completing a randomized clinical trial with two groups: computerized cognitive training using BrainHQ and an active control group that will complete non-cognitive training programs on BrainHQ. Subjects will complete the BICAMS battery at baseline and at the end of their six week intervention. Subjects will be prescribed online activities through BrainHQ to complete 2-3 times a week for approximately 20-30 minutes each. Subjects will also be asked to wear an accelerometer for a week to determine if physical activity affects cognition. The proposed research is significant because MS is diagnosed on average at age 30
Interventions
- DEVICE BrainHQ cognitive training
- DEVICE BrainHQ control games
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2022-06-28 |
| Est. Completion | 2022-10-21 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05345288
The ClinicalTrials.gov registry entry for NCT05345288 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 53 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which BrainHQ cognitive training is the first listed.
NCT05345288 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05345288 about?
NCT05345288 is a clinical study titled "Effect of Computerized Cognitive Training in Persons With MS". Multiple sclerosis (MS) affects approximately one million people in the United States and 2.5 million worldwide. Between one million and 1.75 million persons with MS (PwMS) worldwide are estimated to suffer from cognitive impairment. Unfortunately, there is currently no consensus on the best treatme...
What is the current status of trial NCT05345288?
This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2022-06-28. Estimated completion is 2022-10-21.
What interventions are being tested in trial NCT05345288?
The interventions under investigation include: BrainHQ cognitive training (DEVICE), BrainHQ control games (DEVICE).
Who is sponsoring clinical trial NCT05345288?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
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