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NCT05341700 · ClinicalTrials.gov registry record · NA

Impact Loading Effect on Bone Biomarkers in Female Runners

A NA study, sponsored by Virginia Polytechnic Institute and State University.

Completed
Registry status
NA
Development phase
14
Enrollment target

NCT05341700: Completed NA study, sponsored by Virginia Polytechnic Institute and State University.

NCT05341700 is a NA study that has completed, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05341700, a NA study, has completed, sponsored by Virginia Polytechnic Institute and State University.

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

This study is a randomized, cross-over intervention study that will evaluate the effect of brief, high-impact loading exercises on biomarkers of bone metabolism in energy-restricted female runners. Volunteers will complete two 5-day experimental conditions in a randomized order separated by one menstrual cycle (approximately 3 weeks). Experimental conditions will include a dietary intervention of energy intake equal to 30 kcal/kg of fat-free mass/d using controlled diets and an exercise intervention of daily treadmill running with or without an additional 50 impact loading exercises.

Primary Outcome

Plasma N-terminal propeptide of type 1 procollagen (PINP) was collected from fasted blood samples drawn before and after each 5-day intervention. The enzyme-linked immunosorbent assays (ELISA) were performed on all samples upon study completion.

Interventions

  • BEHAVIORAL Impact Load Exercises
  • BEHAVIORAL No Impact Load Exercises

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2022-08-24
Est. Completion 2024-04-12
Phase NA

What the finished NCT05341700 record still lists

NCT05341700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Impact Load Exercises is the first listed.

NCT05341700 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05341700 about?

NCT05341700 is a clinical study titled "Impact Loading Effect on Bone Biomarkers in Female Runners". This study is a randomized, cross-over intervention study that will evaluate the effect of brief, high-impact loading exercises on biomarkers of bone metabolism in energy-restricted female runners. Volunteers will complete two 5-day experimental conditions in a randomized order separated by one mens...

What is the current status of trial NCT05341700?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2022-08-24. Estimated completion is 2024-04-12.

What interventions are being tested in trial NCT05341700?

The interventions under investigation include: Impact Load Exercises (BEHAVIORAL), No Impact Load Exercises (BEHAVIORAL).

Who is sponsoring clinical trial NCT05341700?

This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05341700's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05341700, the US trial registry maintained by the National Library of Medicine. NCT05341700 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.