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NCT05336968 · ClinicalTrials.gov registry record · Phase 4
Triamcinolone Ketorolac (TriKe) Knee Trial
A Phase 4 study of Osteoarthritis, Knee, sponsored by United Health Services Hospitals.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT05336968: Recruiting Phase 4 study of Osteoarthritis, Knee, sponsored by United Health Services Hospitals.
NCT05336968 is a Phase 4 study of Osteoarthritis, Knee that is actively recruiting participants, run by United Health Services Hospitals. The registered enrollment target is 150 participants, below the 496-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05336968, a Phase 4 study of Osteoarthritis, Knee, is actively recruiting participants, sponsored by United Health Services Hospitals.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Cortisone injections are commonly used in the treatment of osteoarthrosis of the knee, but there are known detriments to cortisone including localized tissue atrophy near the injection site and acceleration of joint degeneration, as well as contraindications, such as uncontrolled diabetes. Ketorolac is a non-steroidal anti-inflammatory with decades of clinical data that is most commonly injected intramuscularly. There is rising interest in using ketorolac as an intra-articular injectant substitute or adjunctive to cortisone. This may potentially improve clinical outcomes or decrease adverse effects. Although intra-articular use of ketorolac is increasing in orthopedics and sports medicine, there is limited data in the literature comparing these two injectants in prospective, randomized trials, and no data that evaluates combining the two injectants. Primary objectives are to evaluate the efficacy of intra-articular ketorolac compared to cortisone on knee osteoarthrosis and to evaluate whether the combination of ketorolac and cortisone is superior to either alone.
Conditions Studied
Interventions
- DRUG Triamcinolone acetonide-Ketorolac-Ropivacaine
Study Locations (1)
New York
- United Health Services Sports Medicine Department - Vestal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2022-09-15 |
| Est. Completion | 2025-12-31 |
| Phase | Phase 4 |
What NCT05336968 shows while recruiting
NCT05336968 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 496-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (70% lower).
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 1 intervention - of which Triamcinolone acetonide-Ketorolac-Ropivacaine is the first listed.
NCT05336968 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05336968 about?
NCT05336968 is a clinical study titled "Triamcinolone Ketorolac (TriKe) Knee Trial". Cortisone injections are commonly used in the treatment of osteoarthrosis of the knee, but there are known detriments to cortisone including localized tissue atrophy near the injection site and acceleration of joint degeneration, as well as contraindications, such as uncontrolled diabetes. Ketorolac...
What is the current status of trial NCT05336968?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 150 participants. The study started on 2022-09-15. Estimated completion is 2025-12-31.
What conditions does trial NCT05336968 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT05336968?
The interventions under investigation include: Triamcinolone acetonide-Ketorolac-Ropivacaine (DRUG).
Who is sponsoring clinical trial NCT05336968?
This trial is sponsored by United Health Services Hospitals, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05336968 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05336968's enrollment target sits among peer trials
150 43rd of 112 higher than 66 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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