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NCT05336409 · ClinicalTrials.gov registry record · Phase 1
A Study of CNTY-101 in Participants With CD19-Positive B-Cell Malignancies
A Phase 1 study, sponsored by Century Therapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT05336409: Clinical Trial Phase 1 study, sponsored by Century Therapeutics.
NCT05336409 is a Phase 1 study that was terminated before completion, run by Century Therapeutics. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05336409, a Phase 1 study, was terminated before completion, sponsored by Century Therapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
ELiPSE-1 is a Phase 1, multi-center, dose-finding study to evaluate the safety, pharmacokinetics, and preliminary efficacy of CNTY-101 in participants with relapsed or refractory cluster of differentiation (CD)19-positive B-cell malignancies.
Interventions
- BIOLOGICAL CNTY-101
- BIOLOGICAL IL-2
- DRUG Lymphodepleting Chemotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2023-01-24 |
| Est. Completion | 2025-07-01 |
| Phase | Phase 1 |
Why NCT05336409 stopped before completion
NCT05336409 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 3 interventions - of which CNTY-101 is the first listed.
NCT05336409 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05336409 about?
NCT05336409 is a clinical study titled "A Study of CNTY-101 in Participants With CD19-Positive B-Cell Malignancies". ELiPSE-1 is a Phase 1, multi-center, dose-finding study to evaluate the safety, pharmacokinetics, and preliminary efficacy of CNTY-101 in participants with relapsed or refractory cluster of differentiation (CD)19-positive B-cell malignancies.
What is the current status of trial NCT05336409?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2023-01-24. Estimated completion is 2025-07-01.
What interventions are being tested in trial NCT05336409?
The interventions under investigation include: CNTY-101 (BIOLOGICAL), IL-2 (BIOLOGICAL), Lymphodepleting Chemotherapy (DRUG).
Who is sponsoring clinical trial NCT05336409?
This trial is sponsored by Century Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05336409's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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