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NCT05335993 · ClinicalTrials.gov registry record · Phase 2
A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.
A Phase 2 study of Peritoneal Cancer and Recurrent Ovarian Cancer, sponsored by CanariaBio.
- Active
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
- 3
- Study locations
NCT05335993: Active Phase 2 study of Peritoneal Cancer and Recurrent Ovarian Cancer, sponsored by CanariaBio.
NCT05335993 is a Phase 2 study of Peritoneal Cancer and Recurrent Ovarian Cancer that is active but no longer recruiting, run by CanariaBio. The registered enrollment target is 10 participants, below the 154-participant average among 32 other Peritoneal Cancer trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05335993, a Phase 2 study of Peritoneal Cancer and Recurrent Ovarian Cancer, is active but no longer recruiting, sponsored by CanariaBio.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
- 3
- Study locations
Study Summary
Study to evaluate the safety and activity of oregovomab and niraparib as a combinatorial immune priming strategy in subjects with platinum sensitive recurrent ovarian cancer.
Primary Outcome
To evaluate anti-tumor activity of oregovomab added to niraparib by Disease Control Rate, defined as the portion of subjects with complete response (CR), partial response (PR) and stable disease (SD) at week 12. The DCR will be determined as defined by RECIST 1.1
Conditions Studied
Interventions
- DRUG Niraparib
- BIOLOGICAL Oregovomab
Study Locations (3)
North Carolina
- Duke Cancer Center - Durham
Oklahoma
- Stephenson Cancer Center- University of Oklahoma Health Sciences Center - Oklahoma City
Virginia
- University of Virginia Health System - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2022-07-25 |
| Est. Completion | 2025-07-30 |
| Phase | Phase 2 |
What the registry record for NCT05335993 still lists
NCT05335993 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 154-participant average among 32 other Peritoneal Cancer trials with a reported enrollment target (94% lower).
The record links to 7 conditions, with Peritoneal Cancer appearing as the primary indexed condition, and to 2 interventions - of which Niraparib is the first listed.
NCT05335993 reports a single indexed study location in North Carolina, Oklahoma, Virginia.
Frequently Asked Questions
What is clinical trial NCT05335993 about?
NCT05335993 is a clinical study titled "A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.". Study to evaluate the safety and activity of oregovomab and niraparib as a combinatorial immune priming strategy in subjects with platinum sensitive recurrent ovarian cancer.
What is the current status of trial NCT05335993?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2022-07-25. Estimated completion is 2025-07-30.
What conditions does trial NCT05335993 study?
This clinical trial studies the following conditions: Peritoneal Cancer, Recurrent Ovarian Cancer, Recurrent Fallopian Tube Cancer, Recurrent Epithelial Cancer of Ovary, Recurrent Epithelial Ovarian Cancer.
What interventions are being tested in trial NCT05335993?
The interventions under investigation include: Niraparib (DRUG), Oregovomab (BIOLOGICAL).
Who is sponsoring clinical trial NCT05335993?
This trial is sponsored by CanariaBio, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05335993 being conducted?
This trial has 3 study locations across North Carolina, Oklahoma, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Peritoneal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05335993's enrollment target sits among peer trials
10 31st of 32 higher than 2 of 32 other Peritoneal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Peritoneal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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