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NCT05332717 · ClinicalTrials.gov registry record · NA
TKA Melatonin and Sleep Quality
A NA study, sponsored by Hospital for Special Surgery, New York.
- Completed
- Registry status
- NA
- Development phase
- 176
- Enrollment target
NCT05332717: Completed NA study, sponsored by Hospital for Special Surgery, New York.
NCT05332717 is a NA study that has completed, run by Hospital for Special Surgery, New York. The registered enrollment target is 176 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05332717, a NA study, has completed, sponsored by Hospital for Special Surgery, New York.
- COMPLETED
- Registry status
- NA
- Development phase
- 176 participants
- Enrollment target
Study Summary
This randomized controlled trial (RCT) will compare the effects of melatonin vs. placebo in patients undergoing primary total knee arthroplasty (TKA). This RCT aims to study the effects melatonin has on sleep quality after TKA. Patients will be blinded to their respective groups and will be instructed to take either 5mg melatonin or a placebo pill (Vitamin C) for 6 weeks postoperative. Sleep quality surveys will be administered preoperatively and post-operative week 6, 90-days and 1 year. Poor sleep quality is a common issue faced by patients undergoing TKA. The goal of this study is see if melatonin can improve postoperative sleep quality, and if so, does improved sleep quality correlate to improvements in other postoperative outcomes.
Primary Outcome
Assessed based on self-reported data collected using the Pittsburgh Sleep Quality Index (PSQI). Minimum Score: 0; Maximum Score: 21. Higher scores indicate a worse outcome.
Interventions
- DIETARY_SUPPLEMENT Melatonin 5 mg
- DIETARY_SUPPLEMENT Placebo (Vitamin C)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 176 participants |
| Start Date | 2022-01-10 |
| Est. Completion | 2022-04-30 |
| Phase | NA |
What the finished NCT05332717 record still lists
NCT05332717 is an interventional study that assigns participants to a tested intervention. The registered 176 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Melatonin 5 mg is the first listed.
NCT05332717 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05332717 about?
NCT05332717 is a clinical study titled "TKA Melatonin and Sleep Quality". This randomized controlled trial (RCT) will compare the effects of melatonin vs. placebo in patients undergoing primary total knee arthroplasty (TKA). This RCT aims to study the effects melatonin has on sleep quality after TKA. Patients will be blinded to their respective groups and will be instruct...
What is the current status of trial NCT05332717?
This trial is currently completed. It is a NA study. The enrollment target is 176 participants. The study started on 2022-01-10. Estimated completion is 2022-04-30.
What interventions are being tested in trial NCT05332717?
The interventions under investigation include: Melatonin 5 mg (DIETARY_SUPPLEMENT), Placebo (Vitamin C) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05332717?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05332717's enrollment target sits among peer trials
176 605th of 2000 higher than 1,391 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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