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NCT05327491 · ClinicalTrials.gov registry record · Phase 1
A Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 Tablets
A Phase 1 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 1
- Development phase
- 146
- Enrollment target
NCT05327491: Completed Phase 1 study, sponsored by Amgen.
NCT05327491 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 146 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (143% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05327491, a Phase 1 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 146 participants
- Enrollment target
Study Summary
The primary objective of the study is to compare the pharmacokinetics (PK) of sotorasib administered orally as 1 tablet under fasted conditions to sotorasib administered orally as 2 tablets under fasted conditions.
Interventions
- DRUG Sotorasib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 146 participants |
| Start Date | 2022-03-21 |
| Est. Completion | 2022-07-17 |
| Phase | Phase 1 |
What the finished NCT05327491 record still lists
NCT05327491 is an interventional study that assigns participants to a tested intervention. The registered 146 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (143% higher).
The record links to 0 conditions, and to 1 intervention - of which Sotorasib is the first listed.
NCT05327491 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05327491 about?
NCT05327491 is a clinical study titled "A Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 Tablets". The primary objective of the study is to compare the pharmacokinetics (PK) of sotorasib administered orally as 1 tablet under fasted conditions to sotorasib administered orally as 2 tablets under fasted conditions.
What is the current status of trial NCT05327491?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 146 participants. The study started on 2022-03-21. Estimated completion is 2022-07-17.
What interventions are being tested in trial NCT05327491?
The interventions under investigation include: Sotorasib (DRUG).
Who is sponsoring clinical trial NCT05327491?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05327491's enrollment target sits among peer trials
146 391st of 2000 higher than 1,610 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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