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NCT05327387 · ClinicalTrials.gov registry record · NA
Model-based Electrical Brain Stimulation
A NA study of Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring, sponsored by University of Southern California.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 2
- Study locations
NCT05327387 is a NA study of Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 25 participants. The trial reports 2 study locations across 1 state.
The verdict
NCT05327387, a NA study of Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring, is actively recruiting participants, sponsored by University of Southern California.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 2
- Study locations
Study Summary
Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them. Also, millions of patients do not respond to current medications or psychotherapy, which makes it critical to find an alternative therapy. Applying electrical stimulation at various brain targets has shown promise but there is a critical need to improve efficacy. Given inter- and intra-subject variabilities in neuropsychiatric disorders, this study aims to enable personalizing the stimulation therapy via i) tracking a patient's own symptoms based on their neural activity, and ii) a model of how their neural activity responds to stimulation therapy. The study will develop the modeling elements needed to realize a model-based personalized system for electrical brain stimulation to achieve this aim. The study will provide proof-of-concept demonstration in epilepsy patients who already have intracranial electroencephalography (iEEG) electrodes implanted for their standard clinical monitoring unrelated to this study, and who consent to being part of the study.
Conditions Studied
Interventions
- OTHER model-based electrical brain stimulation
Study Locations (2)
California
- University of Southern California - Los Angeles
- University of California, San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2022-02-08 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05327387
The ClinicalTrials.gov registry entry for NCT05327387 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring appearing as the primary indexed condition, and to 1 intervention - of which model-based electrical brain stimulation is the first listed.
NCT05327387 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05327387 about?
NCT05327387 is a clinical study titled "Model-based Electrical Brain Stimulation". Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them. Also, millions of patients do not respond to current medications or psychotherapy, which makes it critical to find an alternative therapy. Applying electrical ...
What is the current status of trial NCT05327387?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2022-02-08. Estimated completion is 2026-03-31.
What conditions does trial NCT05327387 study?
This clinical trial studies the following conditions: Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring.
What interventions are being tested in trial NCT05327387?
The interventions under investigation include: model-based electrical brain stimulation (OTHER).
Who is sponsoring clinical trial NCT05327387?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05327387 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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