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NCT05312736 · ClinicalTrials.gov registry record
Gyrate Atrophy Ocular and Systemic Study
A clinical trial of Gyrate Atrophy and Gyrata of Choroid and Retina; Atrophy, sponsored by Jaeb Center for Health Research.
- Active
- Registry status
- 46
- Enrollment target
- 11
- Study locations
NCT05312736: Active study of Gyrate Atrophy and Gyrata of Choroid and Retina; Atrophy, sponsored by Jaeb Center for Health Research.
NCT05312736 is a study of Gyrate Atrophy and Gyrata of Choroid and Retina; Atrophy that is active but no longer recruiting, run by Jaeb Center for Health Research. The registered enrollment target is 46 participants. The trial reports 11 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05312736, a study of Gyrate Atrophy and Gyrata of Choroid and Retina; Atrophy, is active but no longer recruiting, sponsored by Jaeb Center for Health Research.
- ACTIVE NOT RECRUITING
- Registry status
- 46 participants
- Enrollment target
- 11
- Study locations
Study Summary
The Gyrate Atrophy Ocular and Systemic Study characterizes the natural history of ornithine levels and retinal degeneration (RD) associated with disease-causing OAT variants in the presence of standard care dietary treatment regimens over 4 years. The research goal is to understand the impact of OAT mutations on plasma ornithine levels and retinal degeneration. Funding Source- FDA OOPD
Primary Outcome
Measured by Wide Field Fundus Autofluorescence (FAF)
Conditions Studied
Study Locations (11)
Other
- Helsinki University Hospital - Helsinki
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, INSERM-DGOS CIC1423 - Paris
- University of Tuebingen, Centre for Ophthalmology - Tübingen
- Vista Vision Eye Clinic - Brescia
- Moorfields Eye Hospital - London
California
- University of California San Francisco - San Francisco
Maryland
- Johns Hopkins University, Wilmer Eye Institute - Baltimore
Massachusetts
- Harvard Univ., Massachusetts Eye and Ear Infirmary - Boston
Pennsylvania
- University of Pennsylvania - Philadelphia
Minas Gerais
- INRET Clínica e Centro de Pesquisa - Belo Horizonte
Ontario
- University of Toronto, Hospital for Sick Children - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2023-11-21 |
| Est. Completion | 2028-12-31 |
What the registry record for NCT05312736 still lists
NCT05312736 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 46 participants, a relatively small participant target.
The record links to 5 conditions, with Gyrate Atrophy appearing as the primary indexed condition, and to 0 interventions.
NCT05312736 lists 11 locations in 7 states (Other, California, Maryland).
Frequently Asked Questions
What is clinical trial NCT05312736 about?
NCT05312736 is a clinical study titled "Gyrate Atrophy Ocular and Systemic Study". The Gyrate Atrophy Ocular and Systemic Study characterizes the natural history of ornithine levels and retinal degeneration (RD) associated with disease-causing OAT variants in the presence of standard care dietary treatment regimens over 4 years. The research goal is to understand the impact of OAT...
What is the current status of trial NCT05312736?
This trial is currently active not recruiting. The enrollment target is 46 participants. The study started on 2023-11-21. Estimated completion is 2028-12-31.
What conditions does trial NCT05312736 study?
This clinical trial studies the following conditions: Gyrate Atrophy, Gyrata of Choroid and Retina; Atrophy, Ornithine-δ-aminotransferase, OAT, Chorioretinal Degeneration.
Who is sponsoring clinical trial NCT05312736?
This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05312736 being conducted?
This trial has 11 study locations across California, Maryland, Massachusetts, Pennsylvania, Minas Gerais. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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