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NCT05302791 · ClinicalTrials.gov registry record · NA
Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training
A NA study, sponsored by University of Nebraska.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT05302791: Completed NA study, sponsored by University of Nebraska.
NCT05302791 is a NA study that has completed, run by University of Nebraska. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05302791, a NA study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effect of human skeletal muscle temperature during resistance exercise on myogenic and proteolytic signaling. Subjects will perform bilateral resistance exercise bouts at an intensity that should stimulate a muscle growth response in the Vastus Lateralis. During the resistance exercise, the subjects will receive a cold (10°C) intervention on the experimental limb, while receiving a neutral temperature intervention (22°C) on the control limb.
Primary Outcome
RT-qPCR for Forkhead Box O3 (FOXO3a) \[mRNA response FOXO3a\] Fold change calculated using the delta, delta CT method relative to stable reference genes and pre-exercise measures.
Interventions
- OTHER Resistance Exercise
- DEVICE Muscle Cooling
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2022-04-19 |
| Est. Completion | 2022-10-01 |
| Phase | NA |
What the finished NCT05302791 record still lists
NCT05302791 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Resistance Exercise is the first listed.
NCT05302791 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05302791 about?
NCT05302791 is a clinical study titled "Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training". The purpose of this study is to examine the effect of human skeletal muscle temperature during resistance exercise on myogenic and proteolytic signaling. Subjects will perform bilateral resistance exercise bouts at an intensity that should stimulate a muscle growth response in the Vastus Lateralis. ...
What is the current status of trial NCT05302791?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2022-04-19. Estimated completion is 2022-10-01.
What interventions are being tested in trial NCT05302791?
The interventions under investigation include: Resistance Exercise (OTHER), Muscle Cooling (DEVICE).
Who is sponsoring clinical trial NCT05302791?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05302791's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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