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NCT05292040 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3857210 in Healthy Participants

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
10
Enrollment target

NCT05292040: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT05292040 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05292040, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

The main purpose of this study is to evaluate the presence of study drug LY3857210 in the brain measured by positron emission tomography (PET) with the radioligand \[18F\]-LY3818850 in healthy participants. The safety and tolerability of LY3857210 will also be evaluated. The study will last up to approximately 6 weeks for each participant and may include up to four visits to the study center.

Primary Outcome

Change from baseline in brain RO of LY3857210 measured by \[18F\]-LY3818850 PET scan

Interventions

  • DRUG LY3857210

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2022-03-17
Est. Completion 2022-12-14
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT05292040 record still lists

NCT05292040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which LY3857210 is the first listed.

NCT05292040 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05292040 about?

NCT05292040 is a clinical study titled "A Study of LY3857210 in Healthy Participants". The main purpose of this study is to evaluate the presence of study drug LY3857210 in the brain measured by positron emission tomography (PET) with the radioligand \[18F\]-LY3818850 in healthy participants. The safety and tolerability of LY3857210 will also be evaluated. The study will last up to ap...

What is the current status of trial NCT05292040?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2022-03-17. Estimated completion is 2022-12-14.

What interventions are being tested in trial NCT05292040?

The interventions under investigation include: LY3857210 (DRUG).

Who is sponsoring clinical trial NCT05292040?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05292040's enrollment target sits among peer trials

10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05292040, the US trial registry maintained by the National Library of Medicine. NCT05292040 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.