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NCT05289310 · ClinicalTrials.gov registry record · NA
Low Oxygen Exposure and Weight Status
A NA study of Obesity, sponsored by Pennington Biomedical Research Center.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05289310: Recruiting NA study of Obesity, sponsored by Pennington Biomedical Research Center.
NCT05289310 is a NA study of Obesity that is actively recruiting participants, run by Pennington Biomedical Research Center. The registered enrollment target is 60 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05289310, a NA study of Obesity, is actively recruiting participants, sponsored by Pennington Biomedical Research Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of energy balance, following 8 wk of calorie restriction (-500 kcal/d) in combination with either overnight exposure to normobaric hypoxia (8 h/night, 15% FiO2, \~2640 m) or normoxia (8 h/night, 21% FiO2), using a commercially available, in-home tent system, in adults with obesity.
Primary Outcome
Body weight will be measured during the baseline weight maintenance phase (days -14 to 0) and each morning during the study (days 1 to 56) following an overnight fast and morning void, using a calibrated digital scale provided to participants to use at home (A\&D Medical wireless weight scale UC-352BLE, San Jose, CA). Change in body weight will be calculated as: body weight on day 56 - baseline body weight (average of days -14 to 0).
Conditions Studied
Interventions
- OTHER Normobaric hypoxia (NH)
- OTHER Normobaric normoxia (NN)
Study Locations (1)
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-05-16 |
| Est. Completion | 2027-04-30 |
| Phase | NA |
What NCT05289310 shows while recruiting
NCT05289310 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Normobaric hypoxia (NH) is the first listed.
NCT05289310 reports a single indexed study location in Louisiana.
Frequently Asked Questions
What is clinical trial NCT05289310 about?
NCT05289310 is a clinical study titled "Low Oxygen Exposure and Weight Status". The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of energy balance, following 8 wk of calorie restriction (-500 kcal/d) in ...
What is the current status of trial NCT05289310?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-05-16. Estimated completion is 2027-04-30.
What conditions does trial NCT05289310 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT05289310?
The interventions under investigation include: Normobaric hypoxia (NH) (OTHER), Normobaric normoxia (NN) (OTHER).
Who is sponsoring clinical trial NCT05289310?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05289310 being conducted?
This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05289310's enrollment target sits among peer trials
60 642nd of 1053 higher than 374 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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