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NCT05280535 · ClinicalTrials.gov registry record · NA

Dual Use of ENDS and Combustible Cigarettes

A NA study, sponsored by Brown University.

Completed
Registry status
NA
Development phase
82
Enrollment target

NCT05280535: Completed NA study, sponsored by Brown University.

NCT05280535 is a NA study that has completed, run by Brown University. The registered enrollment target is 82 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05280535, a NA study, has completed, sponsored by Brown University.

COMPLETED
Registry status
NA
Development phase
82 participants
Enrollment target

Study Summary

This study investigates the degree to which shared behavioral processes underlie combustible cigarette (CC) and electronic nicotine delivery system (ENDS) use in young adult dual users of these products in both the laboratory and natural environment. The primary processes examined by this study are cue-reactivity, attentional bias, and affect. Laboratory hypotheses are: (1) cue exposure will elicit craving of both CC and ENDS in the laboratory and that product-specific cues will elicit stronger craving for the affiliated products; (2) visual probe effects indicating attentional bias in the laboratory will be observed for smoking and vaping images; and (3) cross-conditioning from the first hypothesis will be associated with heaviness of use of CC and ENDS and product choice. Natural environment hypotheses are: (1) presence of tobacco-related cues in the natural environment will elicit craving and use of these products; (2) reactivity to cues, attentional bias, and cross-product conditioning assessed in the laboratory will be associated with craving and use of tobacco products over and above the effects of cues in the natural environment; and (3) negative affect will strengthen these associations.

Primary Outcome

Visual analog scale ranging from 0-100. Higher scores = more craving.

Interventions

  • BEHAVIORAL Cue Reactivity Task
  • BEHAVIORAL Computerized Visual Dot Probe
  • BEHAVIORAL Choice Task

Trial Details

FieldValue
Enrollment Target 82 participants
Start Date 2022-12-14
Est. Completion 2025-05-20
Phase NA
Brown University

231 total trials

What the finished NCT05280535 record still lists

NCT05280535 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 3 interventions - of which Cue Reactivity Task is the first listed.

NCT05280535 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05280535 about?

NCT05280535 is a clinical study titled "Dual Use of ENDS and Combustible Cigarettes". This study investigates the degree to which shared behavioral processes underlie combustible cigarette (CC) and electronic nicotine delivery system (ENDS) use in young adult dual users of these products in both the laboratory and natural environment. The primary processes examined by this study are ...

What is the current status of trial NCT05280535?

This trial is currently completed. It is a NA study. The enrollment target is 82 participants. The study started on 2022-12-14. Estimated completion is 2025-05-20.

What interventions are being tested in trial NCT05280535?

The interventions under investigation include: Cue Reactivity Task (BEHAVIORAL), Computerized Visual Dot Probe (BEHAVIORAL), Choice Task (BEHAVIORAL).

Who is sponsoring clinical trial NCT05280535?

This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05280535's enrollment target sits among peer trials

82 990th of 2000 higher than 1,009 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05280535, the US trial registry maintained by the National Library of Medicine. NCT05280535 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.