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NCT05275192 · ClinicalTrials.gov registry record · NA
Utilization of a Videoscope in Periodontal Regeneration
A NA study of Chronic Periodontitis, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05275192: Recruiting NA study of Chronic Periodontitis, sponsored by University of Illinois at Chicago.
NCT05275192 is a NA study of Chronic Periodontitis that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05275192, a NA study of Chronic Periodontitis, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Although this therapeutic approach is well established in clinical settings and can rescue teeth with poor or questionable prognosis, MIS approaches often suffer from lack of predictability due to poor intraoral visibility of the bony lesion and inability to confirm thorough removal of etiological factors (plaque/calculus) on tooth surfaces. We seek to investigate whether improved visualization of the surgical field using an FDA approved videoscope (V) improves clinical outcomes. For this pilot study, N=50 (to attain 10/group) age, sex matched, systemically healthy subjects diagnosed with Stage III, Grade B periodontitis, formerly known as severe chronic periodontitis, will be randomly assigned to either the VMIS (Test), MIS (Control 1) or Guided Tissue Regeneration (GTR, Control 2) group. All periodontal therapy will be performed following the Standard of Care for periodontal regeneration to determine if utilization of the videoscope improves clinical and radiographic outcomes. We will examine bone fill using conventional digital periapical radiographs (PAR) and Cone Beam Computed Tomography (CBCT) imaging at 6 and 12 months compared to baseline and collect gingival crevicular fluid (GCF) to compare expression of growth factors and cytokines/chemokines during the healing period. This is a single center treatment study where subjects will be recruited from individuals seeking periodontal treatment at the Graduate Periodontics Clinic, UIC College of Dentistry (COD). Participation of all subjects will end after 12 months and will comprise 7 total visits.
Primary Outcome
Measured in mm as the periodontal probing depth (PD) plus gingival recession (GR).
Conditions Studied
Interventions
- DEVICE Videoscope-assisted periodontal regeneration minimally invasive surgery
- PROCEDURE Periodontal regeneration minimally invasive surgery
- PROCEDURE Guided tissue regeneration surgery
Study Locations (1)
Illinois
- University of Illinois, Chicago, College of Dentistry, Periodontics - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-05-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT05275192 shows while recruiting
NCT05275192 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Chronic Periodontitis appearing as the primary indexed condition, and to 3 interventions - of which Videoscope-assisted periodontal regeneration minimally invasive surgery is the first listed.
NCT05275192 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05275192 about?
NCT05275192 is a clinical study titled "Utilization of a Videoscope in Periodontal Regeneration". Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Although this therapeutic approach is well established in clinical settings and can rescue teeth with po...
What is the current status of trial NCT05275192?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2022-05-01. Estimated completion is 2026-12-31.
What conditions does trial NCT05275192 study?
This clinical trial studies the following conditions: Chronic Periodontitis.
What interventions are being tested in trial NCT05275192?
The interventions under investigation include: Videoscope-assisted periodontal regeneration minimally invasive surgery (DEVICE), Periodontal regeneration minimally invasive surgery (PROCEDURE), Guided tissue regeneration surgery (PROCEDURE).
Who is sponsoring clinical trial NCT05275192?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05275192 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Periodontitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05275192's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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