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NCT05268887 · ClinicalTrials.gov registry record · NA

High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease

A NA study of Parkinson Disease, sponsored by Massachusetts Institute of Technology.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT05268887 is a NA study of Parkinson Disease that is actively recruiting participants, run by Massachusetts Institute of Technology. The registered enrollment target is 40 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05268887, a NA study of Parkinson Disease, is actively recruiting participants, sponsored by Massachusetts Institute of Technology.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Parkinson's disease (PD) impacts different types of neural oscillations in the brain, including beta (13-30Hz) and gamma oscillations (30-80Hz), which contributes to PD's cardinal symptoms of resting tremor, rigidity, bradykinesia (slowness of movement), and gait instability. The investigators' lab has developed a non-invasive method of increasing gamma power in the brain using Gamma Entrainment Using Sensory Stimulation (GENUS) through light, sound, and tactile stimulation devices. For this study, 40 participants with mild Parkinson's disease will be recruited, and the investigators will assess their brain waves with electroencephalogram (EEG) before, during, and after light, sound, and tactile stimulation to determine the safety, feasibility, and optimization of GENUS as a potential therapy in the PD population.

Conditions Studied

Interventions

  • DEVICE GENUS device (Active Settings)
  • DEVICE GENUS device (Sham settings)

Study Locations (1)

Massachusetts

  • Massachusetts Institute of Technology - Cambridge

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-02-09
Est. Completion 2025-11
Phase NA

What the Registry Record Tells You About NCT05268887

The ClinicalTrials.gov registry entry for NCT05268887 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The listed sponsor is Massachusetts Institute of Technology, which has 24 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which GENUS device (Active Settings) is the first listed.

NCT05268887 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05268887 about?

NCT05268887 is a clinical study titled "High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease". Parkinson's disease (PD) impacts different types of neural oscillations in the brain, including beta (13-30Hz) and gamma oscillations (30-80Hz), which contributes to PD's cardinal symptoms of resting tremor, rigidity, bradykinesia (slowness of movement), and gait instability. The investigators' lab ...

What is the current status of trial NCT05268887?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2022-02-09. Estimated completion is 2025-11.

What conditions does trial NCT05268887 study?

This clinical trial studies the following conditions: Parkinson Disease.

What interventions are being tested in trial NCT05268887?

The interventions under investigation include: GENUS device (Active Settings) (DEVICE), GENUS device (Sham settings) (DEVICE).

Who is sponsoring clinical trial NCT05268887?

This trial is sponsored by Massachusetts Institute of Technology, which has 24 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05268887 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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