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NCT05259917 · ClinicalTrials.gov registry record · Phase 3

A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

A Phase 3 study, sponsored by KalVista Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
136
Enrollment target

NCT05259917 is a Phase 3 study that has completed, run by KalVista Pharmaceuticals. The registered enrollment target is 136 participants.

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The verdict

NCT05259917, a Phase 3 study, has completed, sponsored by KalVista Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
136 participants
Enrollment target

Study Summary

This study is a randomized, double-blind, placebo-controlled, phase III, three-way crossover clinical trial evaluating the efficacy and safety of KVD900, in the treatment of hereditary angioedema attacks in adolescent and adult Patients

Interventions

  • DRUG Placebo
  • DRUG KVD900 600 mg
  • DRUG KVD900 300 mg

Trial Details

FieldValue
Enrollment Target 136 participants
Start Date 2022-02-22
Est. Completion 2023-12-31
Phase Phase 3

Sponsor

KalVista Pharmaceuticals

9 total trials

What the Registry Record Tells You About NCT05259917

The ClinicalTrials.gov registry entry for NCT05259917 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is KalVista Pharmaceuticals, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT05259917 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05259917 about?

NCT05259917 is a clinical study titled "A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)". This study is a randomized, double-blind, placebo-controlled, phase III, three-way crossover clinical trial evaluating the efficacy and safety of KVD900, in the treatment of hereditary angioedema attacks in adolescent and adult Patients

What is the current status of trial NCT05259917?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 136 participants. The study started on 2022-02-22. Estimated completion is 2023-12-31.

What interventions are being tested in trial NCT05259917?

The interventions under investigation include: Placebo (DRUG), KVD900 600 mg (DRUG), KVD900 300 mg (DRUG).

Who is sponsoring clinical trial NCT05259917?

This trial is sponsored by KalVista Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.