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NCT05243563 · ClinicalTrials.gov registry record · Phase 2

Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?

A Phase 2 study, sponsored by University of South Alabama.

Terminated
Registry status
Phase 2
Development phase
11
Enrollment target

NCT05243563: Clinical Trial Phase 2 study, sponsored by University of South Alabama.

NCT05243563 is a Phase 2 study that was terminated before completion, run by University of South Alabama. The registered enrollment target is 11 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT05243563, a Phase 2 study, was terminated before completion, sponsored by University of South Alabama.

TERMINATED
Registry status
Phase 2
Development phase
11 participants
Enrollment target

Study Summary

This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.

Primary Outcome

The Skindex-29 is a validated tool to assess impact of a chronic skin condition on a person's quality of life. It has been previously used to describe the effects of a treatment and to compare treatments. Values range from 1 (Never) to 5 (All the time). The higher the score, the worse the outcome.

Interventions

  • DRUG Topical steroid
  • DEVICE MonaLisa Touch

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2022-04-13
Est. Completion 2024-06-03
Phase Phase 2
University of South Alabama

17 total trials

Why NCT05243563 stopped before completion

NCT05243563 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Topical steroid is the first listed.

NCT05243563 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05243563 about?

NCT05243563 is a clinical study titled "Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone?". This study will compare the effects of fractionated CO2 laser plus topical steroids versus topical steroids alone in treatment of lichen sclerosus.

What is the current status of trial NCT05243563?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2022-04-13. Estimated completion is 2024-06-03.

What interventions are being tested in trial NCT05243563?

The interventions under investigation include: Topical steroid (DRUG), MonaLisa Touch (DEVICE).

Who is sponsoring clinical trial NCT05243563?

This trial is sponsored by University of South Alabama, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05243563's enrollment target sits among peer trials

11 1967th of 2000 higher than 33 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05243563, the US trial registry maintained by the National Library of Medicine. NCT05243563 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.