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NCT05223751 · ClinicalTrials.gov registry record · NA
Parasympathetic Augmentation Via Respiratory Training for Patients With Systolic Heart Failure
A NA study, sponsored by Lancaster General Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 65
- Enrollment target
NCT05223751: Clinical Trial NA study, sponsored by Lancaster General Hospital.
NCT05223751 is a NA study that was terminated before completion, run by Lancaster General Hospital. The registered enrollment target is 65 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05223751, a NA study, was terminated before completion, sponsored by Lancaster General Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 65 participants
- Enrollment target
Study Summary
This is a prospective, randomized, controlled clinical trial in which participants with NYHA class II or III and symptomatic Heart Failure with reduced Ejection Fraction (HFrEF) (Ejection Fraction (EF) ≤ 45%) will be assigned to one of two treatment groups: standard of care or breathing therapy.
Primary Outcome
Distance (m) covered in six minutes from baseline to 6 months
Interventions
- BEHAVIORAL Meo Health Breathing and humming exercises
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2022-02-07 |
| Est. Completion | 2025-09-12 |
| Phase | NA |
Why NCT05223751 stopped before completion
NCT05223751 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Meo Health Breathing and humming exercises is the first listed.
NCT05223751 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05223751 about?
NCT05223751 is a clinical study titled "Parasympathetic Augmentation Via Respiratory Training for Patients With Systolic Heart Failure". This is a prospective, randomized, controlled clinical trial in which participants with NYHA class II or III and symptomatic Heart Failure with reduced Ejection Fraction (HFrEF) (Ejection Fraction (EF) ≤ 45%) will be assigned to one of two treatment groups: standard of care or breathing therapy.
What is the current status of trial NCT05223751?
This trial is currently terminated. It is a NA study. The enrollment target is 65 participants. The study started on 2022-02-07. Estimated completion is 2025-09-12.
What interventions are being tested in trial NCT05223751?
The interventions under investigation include: Meo Health Breathing and humming exercises (BEHAVIORAL).
Who is sponsoring clinical trial NCT05223751?
This trial is sponsored by Lancaster General Hospital, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05223751's enrollment target sits among peer trials
65 1144th of 2000 higher than 854 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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