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NCT05204680 · ClinicalTrials.gov registry record · NA
Exercise in Advanced Parkinson's Disease (PD) With Deep Brain Stimulation (DBS)
A NA study, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT05204680 is a NA study that has completed, run by St. Joseph's Hospital and Medical Center, Phoenix. The registered enrollment target is 11 participants.
The verdict
NCT05204680, a NA study, has completed, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
This project is a 3-month prospective study assessing the immediate and long-term changes associated with aerobic exercise in quality-of-life measures, nonmotor scores, brief neuropsychological batteries, and local field potentials (LFPs) in those with Parkinson's Disease (PD) who have undergone deep brain stimulation (DBS) surgery for management of their symptoms. In this study, the investigators will assess the feasibility of an aerobic exercise regimen in those with advanced PD and DBS, characterize the immediate and long-term changes in neuronal activity with exercise in PD, and assess the nonmotor impact of exercise in individuals with advanced PD and DBS. The investigators will recruit individuals who are not regular exercisers and develop an individualized 3-month exercise plan with the assistance of physical therapists, using heart rate targets for moderate exercise. Outcomes will be measured at baseline and following 3-months of regular exercise. Field potentials will be noted at baseline, during exercise every 2 weeks, and then a final baseline at the end of 3 months in on-medication and on-stimulation states. This will allow for characterization of field potential changes over time both during exercise as efficiency improves as well as impact on baseline neuronal activity in the resting state. This study is novel in that most aerobic exercise studies target early PD subjects and rarely include those who have undergone DBS surgery. The study will specifically focus on the feasibility of developing an aerobic exercise regimen in those with more advanced disease as well as gathering preliminary data on the impact it will have on motor and nonmotor features in this cohort. In addition to the clinical outcomes, investigators are now able to capture neuronal activity with novel FDA-approved DBS technology, allowing us to non-invasively monitor real-time changes in the basal ganglia in those who have undergone DBS surgery. This study will also aim to characteri
Interventions
- BEHAVIORAL Aerobic Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2023-10-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05204680
The ClinicalTrials.gov registry entry for NCT05204680 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Aerobic Exercise is the first listed.
NCT05204680 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05204680 about?
NCT05204680 is a clinical study titled "Exercise in Advanced Parkinson's Disease (PD) With Deep Brain Stimulation (DBS)". This project is a 3-month prospective study assessing the immediate and long-term changes associated with aerobic exercise in quality-of-life measures, nonmotor scores, brief neuropsychological batteries, and local field potentials (LFPs) in those with Parkinson's Disease (PD) who have undergone dee...
What is the current status of trial NCT05204680?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2022-06-01. Estimated completion is 2023-10-31.
What interventions are being tested in trial NCT05204680?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT05204680?
This trial is sponsored by St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total clinical trials registered on ClinicalTrials.gov.
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