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NCT05185180 · ClinicalTrials.gov registry record
Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome
A clinical trial of Chronic Pelvic Pain, sponsored by Northwestern University.
- Active
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT05185180: Active study of Chronic Pelvic Pain, sponsored by Northwestern University.
NCT05185180 is a study of Chronic Pelvic Pain that is active but no longer recruiting, run by Northwestern University. The registered enrollment target is 50 participants, below the 331-participant average among 8 other Chronic Pelvic Pain trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05185180, a study of Chronic Pelvic Pain, is active but no longer recruiting, sponsored by Northwestern University.
- ACTIVE NOT RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This study seeks to identify defects in immune activation or regulation that may affect a subset of patients with CP/CPPS. This subset appears to have a reduced ability to mount a regulatory immune response, while simultaneously eliciting an exaggerated activated immune response. The defects that we demonstrate appear to be linked to altered methylation of genes involved in both immune regulation and immune activation. The aims of this study will provide definitive evidence of a role for epigenetic changes in immune cells in patients with CP/CPPS.
Primary Outcome
Percent of methylation of genes involved in inflammation and regulation
Conditions Studied
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-10-11 |
| Est. Completion | 2025-12-11 |
What the registry record for NCT05185180 still lists
NCT05185180 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 331-participant average among 8 other Chronic Pelvic Pain trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Chronic Pelvic Pain appearing as the primary indexed condition, and to 0 interventions.
NCT05185180 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05185180 about?
NCT05185180 is a clinical study titled "Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome". This study seeks to identify defects in immune activation or regulation that may affect a subset of patients with CP/CPPS. This subset appears to have a reduced ability to mount a regulatory immune response, while simultaneously eliciting an exaggerated activated immune response. The defects that we...
What is the current status of trial NCT05185180?
This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2021-10-11. Estimated completion is 2025-12-11.
What conditions does trial NCT05185180 study?
This clinical trial studies the following conditions: Chronic Pelvic Pain.
Who is sponsoring clinical trial NCT05185180?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05185180 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pelvic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05185180's enrollment target sits among peer trials
50 7th of 8 higher than 2 of 8 other Chronic Pelvic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pelvic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL)
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-
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-
Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial
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Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
RECRUITING · NA
-
Vaginal Photobiomodulation for Chronic Pelvic Pain
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-
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