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NCT05181995 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of 50 mg NYX-783 QD vs. Placebo in PTSD
A Phase 2 study, sponsored by Aptinyx.
- Terminated
- Registry status
- Phase 2
- Development phase
- 121
- Enrollment target
NCT05181995: Clinical Trial Phase 2 study, sponsored by Aptinyx.
NCT05181995 is a Phase 2 study that was terminated before completion, run by Aptinyx. The registered enrollment target is 121 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05181995, a Phase 2 study, was terminated before completion, sponsored by Aptinyx.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 121 participants
- Enrollment target
Study Summary
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of 50 mg NYX-783 Once Daily Compared to Placebo in Participants with Post-Traumatic Stress Disorder (PTSD)
Primary Outcome
Change from Baseline in CAPS-5
Interventions
- DRUG Placebo
- DRUG NYX-783
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2021-12-13 |
| Est. Completion | 2023-03-30 |
| Phase | Phase 2 |
Why NCT05181995 stopped before completion
NCT05181995 is an interventional study that assigns participants to a tested intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05181995 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05181995 about?
NCT05181995 is a clinical study titled "Safety and Efficacy of 50 mg NYX-783 QD vs. Placebo in PTSD". A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of 50 mg NYX-783 Once Daily Compared to Placebo in Participants with Post-Traumatic Stress Disorder (PTSD)
What is the current status of trial NCT05181995?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 121 participants. The study started on 2021-12-13. Estimated completion is 2023-03-30.
What interventions are being tested in trial NCT05181995?
The interventions under investigation include: Placebo (DRUG), NYX-783 (DRUG).
Who is sponsoring clinical trial NCT05181995?
This trial is sponsored by Aptinyx, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05181995's enrollment target sits among peer trials
121 567th of 2000 higher than 1,432 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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