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NCT05165654 · ClinicalTrials.gov registry record · NA
Improving Hallucinations by Targeting the rSTS With tES
A NA study, sponsored by Beth Israel Deaconess Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT05165654 is a NA study that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 12 participants.
The verdict
NCT05165654, a NA study, has completed, sponsored by Beth Israel Deaconess Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
Hallucinations are a core diagnostic feature of psychotic disorders. They involve different sensory modalities, including auditory, visual, olfactory, tactile, and gustatory hallucinations, among others. Hallucinations occur in multiple different neurological and psychiatric illnesses and can be refractory to existing treatments. Auditory hallucinations and visual hallucinations are found across diagnostic categories of psychotic disorders (schizophrenia, schizoaffective, bipolar disorder). Despite visual hallucinations being approximately half as frequent as auditory hallucinations, they almost always co-occur with auditory hallucinations, and are linked to a more severe psychopathological profile. Auditory and visual hallucinations at baseline also predict higher disability, risk of relapse and duration of psychosis after 1 and 2 years, especially when they occur in combination. Using a newly validated technique termed lesion network mapping, researchers demonstrated that focal brain lesions connected to the right superior temporal sulcus (rSTS) plays a causal role in the development of hallucinations. The rSTS receives convergent somatosensory, auditory, and visual inputs, and is regarded as a site for multimodal sensory integration. Here the investigators aim to answer the question whether noninvasive brain stimulation when optimally targeted to the rSTS can improve brain activity, sensory integration, and hallucinations.
Interventions
- DEVICE Transcranial Electrical Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2025-06-23 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05165654
The ClinicalTrials.gov registry entry for NCT05165654 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Transcranial Electrical Stimulation is the first listed.
NCT05165654 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05165654 about?
NCT05165654 is a clinical study titled "Improving Hallucinations by Targeting the rSTS With tES". Hallucinations are a core diagnostic feature of psychotic disorders. They involve different sensory modalities, including auditory, visual, olfactory, tactile, and gustatory hallucinations, among others. Hallucinations occur in multiple different neurological and psychiatric illnesses and can be ref...
What is the current status of trial NCT05165654?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2021-11-01. Estimated completion is 2025-06-23.
What interventions are being tested in trial NCT05165654?
The interventions under investigation include: Transcranial Electrical Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05165654?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
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