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NCT05161780 · ClinicalTrials.gov registry record · Phase 1
Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation
A Phase 1 study of Irrigation, sponsored by Carl Snyderman.
- Completed
- Registry status
- Phase 1
- Development phase
- 47
- Enrollment target
- 1
- Study location
NCT05161780: Completed Phase 1 study of Irrigation, sponsored by Carl Snyderman.
NCT05161780 is a Phase 1 study of Irrigation that has completed, run by Carl Snyderman. The registered enrollment target is 47 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05161780, a Phase 1 study of Irrigation, has completed, sponsored by Carl Snyderman.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 47 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to determine whether Normal Saline or Lactated Ringer's irrigation is superior in maintaining superior endoscopic surgical field clarity in surgery for pituitary adenoma.
Primary Outcome
Rating for each of the three recorded video clips per patient following tumor ablation. The Boezaart is an ordinal scale 0 = No bleeding 1 = Minimal bleeding: Not a surgical nuisance and no suction required 2 = Mild bleeding: Occasional suction required, but does not affect dissection 3 = Moderate bleeding: Slightly compromises surgical field, frequent suction required 4 = Severe bleeding: Significantly compromises surgical field, frequent suction required, bleeding threat field just after remov
Conditions Studied
Interventions
- DRUG Normal Saline
- DRUG Lactated Ringer's Irrigation
Study Locations (1)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 47 participants |
| Start Date | 2022-02-09 |
| Est. Completion | 2024-06-13 |
| Phase | Phase 1 |
What the finished NCT05161780 record still lists
NCT05161780 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower).
The record links to 1 condition, with Irrigation appearing as the primary indexed condition, and to 2 interventions - of which Normal Saline is the first listed.
NCT05161780 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05161780 about?
NCT05161780 is a clinical study titled "Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation". This study is designed to determine whether Normal Saline or Lactated Ringer's irrigation is superior in maintaining superior endoscopic surgical field clarity in surgery for pituitary adenoma.
What is the current status of trial NCT05161780?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2022-02-09. Estimated completion is 2024-06-13.
What conditions does trial NCT05161780 study?
This clinical trial studies the following conditions: Irrigation.
What interventions are being tested in trial NCT05161780?
The interventions under investigation include: Normal Saline (DRUG), Lactated Ringer's Irrigation (DRUG).
Who is sponsoring clinical trial NCT05161780?
This trial is sponsored by Carl Snyderman, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05161780 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05161780's enrollment target sits among peer trials
47 1053rd of 2000 higher than 943 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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