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NCT05160129 · ClinicalTrials.gov registry record · NA
Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder
A NA study of Obsessive Compulsive Disorder (OCD), sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05160129: Recruiting NA study of Obsessive Compulsive Disorder (OCD), sponsored by Icahn School of Medicine at Mount Sinai.
NCT05160129 is a NA study of Obsessive Compulsive Disorder (OCD) that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 20 participants, below the 242-participant average among 12 other Obsessive Compulsive Disorder (OCD) trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05160129, a NA study of Obsessive Compulsive Disorder (OCD), is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Deep brain stimulation (DBS) is an effective treatment for people suffering from severe obsessive-compulsive disorder (OCD) whose symptoms have failed to improve after years and multiple methods of intervention. An effective DBS target for OCD is the anterior limb of the internal capsule (ALIC) brain region. On average 60% of all OCD patients have a clinically significant response to ALIC DBS. However, ALIC DBS may become even more effective with the ability to predict which specific ALIC connections in the brain need to be stimulated for each individual OCD patient. This study therefore investigates personalized stimulation to the ALIC that allows for precise modulation of brain circuits associated with individual OCD symptoms. The study aims to specify the ideal anatomical target for ALIC DBS for maximum therapeutic benefit in each patient.
Primary Outcome
This scale measures change in OCD symptom severity. Full scale from from 0 - 40 with higher score indicating more severe symptoms.
Conditions Studied
Interventions
- DEVICE Selective focal stimulation of ALIC-pathways
Study Locations (1)
New York
- Mount Sinai West - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-08-13 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What NCT05160129 shows while recruiting
NCT05160129 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 242-participant average among 12 other Obsessive Compulsive Disorder (OCD) trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Obsessive Compulsive Disorder (OCD) appearing as the primary indexed condition, and to 1 intervention - of which Selective focal stimulation of ALIC-pathways is the first listed.
NCT05160129 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05160129 about?
NCT05160129 is a clinical study titled "Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder". Deep brain stimulation (DBS) is an effective treatment for people suffering from severe obsessive-compulsive disorder (OCD) whose symptoms have failed to improve after years and multiple methods of intervention. An effective DBS target for OCD is the anterior limb of the internal capsule (ALIC) brai...
What is the current status of trial NCT05160129?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2021-08-13. Estimated completion is 2026-03-31.
What conditions does trial NCT05160129 study?
This clinical trial studies the following conditions: Obsessive Compulsive Disorder (OCD).
What interventions are being tested in trial NCT05160129?
The interventions under investigation include: Selective focal stimulation of ALIC-pathways (DEVICE).
Who is sponsoring clinical trial NCT05160129?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05160129 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obsessive Compulsive Disorder (OCD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05160129's enrollment target sits among peer trials
20 10th of 12 higher than 3 of 12 other Obsessive Compulsive Disorder (OCD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obsessive Compulsive Disorder (OCD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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