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NCT05240924 · ClinicalTrials.gov registry record · NA

ERP to Improve Functioning in Veterans With OCD

A NA study of Obsessive Compulsive Disorder (OCD) and Comorbid Post-Traumatic Stress Disorder and OCD, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
160
Enrollment target
18
Study locations

NCT05240924 is a NA study of Obsessive Compulsive Disorder (OCD) and Comorbid Post-Traumatic Stress Disorder and OCD that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 160 participants, below the 230-participant average among 12 other Obsessive Compulsive Disorder (OCD) trials with a reported enrollment target (30% lower). The trial reports 18 study locations across 8 states.

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The verdict

NCT05240924, a NA study of Obsessive Compulsive Disorder (OCD) and Comorbid Post-Traumatic Stress Disorder and OCD, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
160 participants
Enrollment target
18
Study locations

Study Summary

Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD. Primary and secondary aims will examine whether Veterans' functioning, quality of life, and OCD symptoms differ between the ERP and control in the full sample of Veterans with OCD, and in the half of the sample with both OCD and PTSD. The tertiary aim is to conduct a mixed-methods formative evaluation of the implementation potential of ERP in VA mental health settings.

Conditions Studied

Obsessive Compulsive Disorder (OCD) Comorbid Post-Traumatic Stress Disorder and OCD

Interventions

  • BEHAVIORAL Exposure and Response Prevention
  • OTHER Stress Management Training

Study Locations (18)

New York

  • VA Western New York Healthcare System, Buffalo, NY - Buffalo
  • VA NY Harbor Healthcare System, New York, NY - New York
  • Northport VA Medical Center, Northport, NY - Northport
  • James J. Peters VA Medical Center, Bronx, NY - The Bronx

North Carolina

  • Asheville VA Medical Center, Asheville, NC - Asheville
  • Durham VA Medical Center, Durham, NC - Durham
  • Fayetteville VA Medical Center, Fayetteville, NC - Fayetteville
  • Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC - Salisbury

Virginia

  • Hampton VA Medical Center, Hampton, VA - Hampton
  • Hunter Holmes McGuire VA Medical Center, Richmond, VA - Richmond
  • Salem VA Medical Center, Salem, VA - Salem

Oregon

  • VA Roseburg Healthcare System, Roseburg, OR - Roseburg
  • VA Southern Oregon Rehabilitation Center and Clinics, White City, OR - White City

Washington

  • Spokane VA Medical Center, Spokane, WA - Spokane
  • Jonathan M. Wainwright Memorial VA Medical Center, Walla Walla, WA - Walla Walla

New Jersey

  • East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ - East Orange

South Carolina

  • Ralph H. Johnson VA Medical Center, Charleston, SC - Charleston

Texas

  • Michael E. DeBakey VA Medical Center, Houston, TX - Houston

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2022-10-03
Est. Completion 2026-05-31
Phase NA

Sponsor

VA Office of Research and Development

1,668 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05240924

The ClinicalTrials.gov registry entry for NCT05240924 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 230-participant average among 12 other Obsessive Compulsive Disorder (OCD) trials with a reported enrollment target (30% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Obsessive Compulsive Disorder (OCD) appearing as the primary indexed condition, and to 2 interventions - of which Exposure and Response Prevention is the first listed.

NCT05240924 reports 18 study locations spanning 8 distinct geographic areas - top geographies include New York, North Carolina, Virginia.

Frequently Asked Questions

What is clinical trial NCT05240924 about?

NCT05240924 is a clinical study titled "ERP to Improve Functioning in Veterans With OCD". Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP am...

What is the current status of trial NCT05240924?

This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2022-10-03. Estimated completion is 2026-05-31.

What conditions does trial NCT05240924 study?

This clinical trial studies the following conditions: Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD.

What interventions are being tested in trial NCT05240924?

The interventions under investigation include: Exposure and Response Prevention (BEHAVIORAL), Stress Management Training (OTHER).

Who is sponsoring clinical trial NCT05240924?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05240924 being conducted?

This trial has 18 study locations across New Jersey, New York, North Carolina, Oregon, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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