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NCT05151484 · ClinicalTrials.gov registry record · Phase 4
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
A Phase 4 study of Age-Related Osteoporosis, sponsored by Madhumathi Rao.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05151484: Recruiting Phase 4 study of Age-Related Osteoporosis, sponsored by Madhumathi Rao.
NCT05151484 is a Phase 4 study of Age-Related Osteoporosis that is actively recruiting participants, run by Madhumathi Rao. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05151484, a Phase 4 study of Age-Related Osteoporosis, is actively recruiting participants, sponsored by Madhumathi Rao.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined. Current treatment options do not account for differences between age-related and estrogen deficiency related osteoporosis, because of the need for bone biopsies for determination. This study will establish a paradigm-shifting individualized treatment protocol for age-related osteoporosis and a non-invasive method for its determination, thereby reducing the major health problems and enormous burden on society and the elderly related to this disease.
Primary Outcome
Percent change in mineral bone density absolute values of the lumbar spine measured by DXA at baseline and at one year.
Conditions Studied
Interventions
- DRUG Teriparatide
- DRUG Alendronate
Study Locations (1)
Kentucky
- University of Kentucky - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-03-21 |
| Est. Completion | 2026-08-31 |
| Phase | Phase 4 |
What NCT05151484 shows while recruiting
NCT05151484 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Age-Related Osteoporosis appearing as the primary indexed condition, and to 2 interventions - of which Teriparatide is the first listed.
NCT05151484 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT05151484 about?
NCT05151484 is a clinical study titled "Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover". Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined. Current treatment options do not account for differences between age-related and estrogen deficiency related osteoporosis, because of ...
What is the current status of trial NCT05151484?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2022-03-21. Estimated completion is 2026-08-31.
What conditions does trial NCT05151484 study?
This clinical trial studies the following conditions: Age-Related Osteoporosis.
What interventions are being tested in trial NCT05151484?
The interventions under investigation include: Teriparatide (DRUG), Alendronate (DRUG).
Who is sponsoring clinical trial NCT05151484?
This trial is sponsored by Madhumathi Rao, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05151484 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Age-Related Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05151484's enrollment target sits among peer trials
60 1125th of 2000 higher than 800 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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