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NCT05134337 · ClinicalTrials.gov registry record · Phase 1
Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants
A Phase 1 study, sponsored by Loxo Oncology.
- Completed
- Registry status
- Phase 1
- Development phase
- 27
- Enrollment target
NCT05134337: Completed Phase 1 study, sponsored by Loxo Oncology.
NCT05134337 is a Phase 1 study that has completed, run by Loxo Oncology. The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05134337, a Phase 1 study, has completed, sponsored by Loxo Oncology.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 27 participants
- Enrollment target
Study Summary
The main purpose of this study is to learn about how itraconazole and rifampin affect LOXO-305 in healthy participants. Participation could last about 8 weeks.
Primary Outcome
Cmax of LOXO-305
Interventions
- DRUG Rifampin
- DRUG Itraconazole
- DRUG LOXO-305
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2020-02-12 |
| Est. Completion | 2020-10-30 |
| Phase | Phase 1 |
What the finished NCT05134337 record still lists
NCT05134337 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which Rifampin is the first listed.
NCT05134337 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05134337 about?
NCT05134337 is a clinical study titled "Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants". The main purpose of this study is to learn about how itraconazole and rifampin affect LOXO-305 in healthy participants. Participation could last about 8 weeks.
What is the current status of trial NCT05134337?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2020-02-12. Estimated completion is 2020-10-30.
What interventions are being tested in trial NCT05134337?
The interventions under investigation include: Rifampin (DRUG), Itraconazole (DRUG), LOXO-305 (DRUG).
Who is sponsoring clinical trial NCT05134337?
This trial is sponsored by Loxo Oncology, which has 14 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05134337's enrollment target sits among peer trials
27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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