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NCT05126563 · ClinicalTrials.gov registry record · Phase 2

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome

A Phase 2 study of Post COVID-19 Syndrome, sponsored by Hope Biosciences Research Foundation.

Completed
Registry status
Phase 2
Development phase
79
Enrollment target
1
Study location

NCT05126563: Completed Phase 2 study of Post COVID-19 Syndrome, sponsored by Hope Biosciences Research Foundation.

NCT05126563 is a Phase 2 study of Post COVID-19 Syndrome that has completed, run by Hope Biosciences Research Foundation. The registered enrollment target is 79 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05126563, a Phase 2 study of Post COVID-19 Syndrome, has completed, sponsored by Hope Biosciences Research Foundation.

COMPLETED
Registry status
Phase 2
Development phase
79 participants
Enrollment target
1
Study location

Study Summary

This study will enroll up to 80 subjects with Chronic Post COVID-19 Syndrome. Subjects will receive four intravenous injections of either allogeneic HB-adMSC's or a placebo over 10 weeks with two follow-up visits and an end of study visit at week 26.

Primary Outcome

Clinically significant changes in Visual Analog Scale - Extreme fatigue. A VAS is a straight line with two end points that represent the extremes of a range. This VAS used to measure extreme fatigue has one end labeled "no fatigue" and the other end labeled "worst fatigue". The patient then marks a point on the line to indicate their current level of fatigue. The minimum score is a 0 and the maximum score is a 10. A higher score indicates a worse outcome (fatigue).

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL HB-adMSCs (allogeneic)

Study Locations (1)

Texas

  • Hope Biosciences Research Foundation - Sugar Land

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2022-02-02
Est. Completion 2024-04-02
Phase Phase 2

What the finished NCT05126563 record still lists

NCT05126563 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower).

The record links to 1 condition, with Post COVID-19 Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05126563 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05126563 about?

NCT05126563 is a clinical study titled "Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome". This study will enroll up to 80 subjects with Chronic Post COVID-19 Syndrome. Subjects will receive four intravenous injections of either allogeneic HB-adMSC's or a placebo over 10 weeks with two follow-up visits and an end of study visit at week 26.

What is the current status of trial NCT05126563?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 79 participants. The study started on 2022-02-02. Estimated completion is 2024-04-02.

What conditions does trial NCT05126563 study?

This clinical trial studies the following conditions: Post COVID-19 Syndrome.

What interventions are being tested in trial NCT05126563?

The interventions under investigation include: Placebo (OTHER), HB-adMSCs (allogeneic) (BIOLOGICAL).

Who is sponsoring clinical trial NCT05126563?

This trial is sponsored by Hope Biosciences Research Foundation, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05126563 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Post COVID-19 Syndrome

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05126563's enrollment target sits among peer trials

79 884th of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05126563, the US trial registry maintained by the National Library of Medicine. NCT05126563 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.