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Post-Concussion Musculoskeletal Injury Risks
NCT05122728 · View on ClinicalTrials.gov ↗
Study Summary
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19 years and account for 22% of all combat casualties. Concussion, a mild form of TBI, increases MSKI risk in physically active individuals, including Service Members. The overall goal of the study is to identify the neuromuscular control mechanisms that increase MSKI risk following concussion. It is hypothesized that concussed individuals will display abnormal neuromuscular function that increases MSKI risk, as compared to non-concussed controls. The study will employ a multi-center, prospective, case-matched control observational study to identify the differences in neuromuscular function following concussion that may contribute to increased MSKI risk. Once the neuromuscular control mechanisms that increase MSKI risk following concussion are identified, targeted risk mitigation strategies can be developed to reduce MSKI risk.
Conditions Studied
Interventions
- OTHER Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment
Study Locations (3)
Georgia
- University of Georgia — Athens
Maryland
- Walter Reed National Military Medical Center — Bethesda
North Carolina
- Womack Army Medical Center — Fort Bragg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 148 participants |
| Start Date | 2022-10-20 |
| Est. Completion | 2027-09-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05122728
The ClinicalTrials.gov registry entry for NCT05122728 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 148 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Walter Reed National Military Medical Center, which has 73 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Musculoskeletal Injury appearing as the primary indexed condition, and to 1 intervention — of which Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05122728 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Georgia, Maryland, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05122728 about?
NCT05122728 is a clinical study titled "Post-Concussion Musculoskeletal Injury Risks". Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19 years and account for 22% of all combat casualties. Concussion, a mild fo...
What is the current status of trial NCT05122728?
This trial is currently recruiting. The enrollment target is 148 participants. The study started on 2022-10-20. Estimated completion is 2027-09-30.
What conditions does trial NCT05122728 study?
This clinical trial studies the following conditions: Musculoskeletal Injury. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05122728?
The interventions under investigation include: Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05122728?
This trial is sponsored by Walter Reed National Military Medical Center, which has 73 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05122728 being conducted?
This trial has 3 study locations across Georgia, Maryland, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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