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NCT05117931 · ClinicalTrials.gov registry record · Phase 2
A Study of Amivantamab in People With Esophagogastric Cancer
A Phase 2 study of Esophagogastric Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
- 9
- Study locations
NCT05117931: Active Phase 2 study of Esophagogastric Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT05117931 is a Phase 2 study of Esophagogastric Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 25 participants, below the 78-participant average among 5 other Esophagogastric Cancer trials with a reported enrollment target (68% lower). The trial reports 9 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05117931, a Phase 2 study of Esophagogastric Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
- 9
- Study locations
Study Summary
The purpose of this study is to see whether the study drug, amivantamab, is an effective treatment for people with EGFR- or MET-amplified esophagogastric cancer. The researchers will also look at whether amivantamab is a safe treatment that causes few or mild side effects in participants.
Primary Outcome
ORR; defined as complete response (CR) or partial response (PR)) by RECIST 1.1 criteria
Conditions Studied
Interventions
- DRUG Amivantamab
Study Locations (9)
New York
- Memorial Sloan Kettering Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (Limited protocol activities) - Rockville Centre
New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited protocol activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited protocol activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
California
- University of California, Irvine - Irvine
Massachusetts
- Massachusetts General Hospital (Data Collection Only) - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2021-12-02 |
| Est. Completion | 2026-11 |
| Phase | Phase 2 |
What the registry record for NCT05117931 still lists
NCT05117931 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 78-participant average among 5 other Esophagogastric Cancer trials with a reported enrollment target (68% lower).
The record links to 1 condition, with Esophagogastric Cancer appearing as the primary indexed condition, and to 1 intervention - of which Amivantamab is the first listed.
NCT05117931 lists 9 locations in 4 states (New York, New Jersey, California).
Frequently Asked Questions
What is clinical trial NCT05117931 about?
NCT05117931 is a clinical study titled "A Study of Amivantamab in People With Esophagogastric Cancer". The purpose of this study is to see whether the study drug, amivantamab, is an effective treatment for people with EGFR- or MET-amplified esophagogastric cancer. The researchers will also look at whether amivantamab is a safe treatment that causes few or mild side effects in participants.
What is the current status of trial NCT05117931?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2021-12-02. Estimated completion is 2026-11.
What conditions does trial NCT05117931 study?
This clinical trial studies the following conditions: Esophagogastric Cancer.
What interventions are being tested in trial NCT05117931?
The interventions under investigation include: Amivantamab (DRUG).
Who is sponsoring clinical trial NCT05117931?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05117931 being conducted?
This trial has 9 study locations across California, Massachusetts, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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