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NCT05111002 · ClinicalTrials.gov registry record · Phase 1
Lefamulin for M. Genitalium Treatment Failures
A Phase 1 study, sponsored by University of Washington.
- Terminated
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT05111002: Clinical Trial Phase 1 study, sponsored by University of Washington.
NCT05111002 is a Phase 1 study that was terminated before completion, run by University of Washington. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05111002, a Phase 1 study, was terminated before completion, sponsored by University of Washington.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this drug study is to find out whether the antibiotic lefamulin (trade name Xenleta) will cure Mycoplasma genitalium infections that have not been cured by prior antibiotics while finding out whether it is more effective if the antibiotic doxycycline is taken first.
Primary Outcome
Defined as a negative Aptima Mycoplasma genitalium test 21-28 days after completion of the lefamulin
Interventions
- DRUG Doxycycline
- DRUG Lefamulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2022-04-22 |
| Est. Completion | 2023-11-30 |
| Phase | Phase 1 |
Why NCT05111002 stopped before completion
NCT05111002 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Doxycycline is the first listed.
NCT05111002 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05111002 about?
NCT05111002 is a clinical study titled "Lefamulin for M. Genitalium Treatment Failures". The purpose of this drug study is to find out whether the antibiotic lefamulin (trade name Xenleta) will cure Mycoplasma genitalium infections that have not been cured by prior antibiotics while finding out whether it is more effective if the antibiotic doxycycline is taken first.
What is the current status of trial NCT05111002?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2022-04-22. Estimated completion is 2023-11-30.
What interventions are being tested in trial NCT05111002?
The interventions under investigation include: Doxycycline (DRUG), Lefamulin (DRUG).
Who is sponsoring clinical trial NCT05111002?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05111002's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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