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NCT05081882 · ClinicalTrials.gov registry record · Phase 2

Reducing Tobacco-associated Lung Cancer Risk: A Randomized Clinical Trial of AB-free Kava

A Phase 2 study of Smoking, sponsored by University of Florida.

Active
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT05081882 is a Phase 2 study of Smoking that is active but no longer recruiting, run by University of Florida. The registered enrollment target is 20 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05081882, a Phase 2 study of Smoking, is active but no longer recruiting, sponsored by University of Florida.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Tobacco use is the leading cause of many preventable diseases, particularly lung cancer. Based on the national cancer data in 2020, Florida has the highest lung cancer incidence (18,150 cases) with the most deaths (10,580 deaths) among all the states in the United States. Unfortunately, around 16% of adults in Florida continue to smoke cigarettes due to its addictive nature and the limited success of current cessation strategies. Therefore, there is an unmet and urgent need for novel interventions to improve the success of tobacco cessation. If such an intervention can reduce tobacco-associated lung carcinogenesis, that will be more desirable. The ultimate goal of this study is to develop a safe and effective kava-based intervention to enable tobacco cessation and reduce lung cancer risk, which will improve the health of Floridians. This study will evaluate the compliance with a daily kava regimen among active smokers who have no intention to quit smoking. This study will also investigate whether kava use can reduce tobacco use and dependence, as well as tobacco-associated lung carcinogenesis.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Kava

Study Locations (1)

Florida

  • University of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2022-06-09
Est. Completion 2026-12
Phase Phase 2

Sponsor

University of Florida

1,106 total trials

What the Registry Record Tells You About NCT05081882

The ClinicalTrials.gov registry entry for NCT05081882 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (96% lower). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Smoking appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05081882 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT05081882 about?

NCT05081882 is a clinical study titled "Reducing Tobacco-associated Lung Cancer Risk: A Randomized Clinical Trial of AB-free Kava". Tobacco use is the leading cause of many preventable diseases, particularly lung cancer. Based on the national cancer data in 2020, Florida has the highest lung cancer incidence (18,150 cases) with the most deaths (10,580 deaths) among all the states in the United States. Unfortunately, around 16% o...

What is the current status of trial NCT05081882?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-06-09. Estimated completion is 2026-12.

What conditions does trial NCT05081882 study?

This clinical trial studies the following conditions: Smoking.

What interventions are being tested in trial NCT05081882?

The interventions under investigation include: Placebo (DRUG), Kava (DRUG).

Who is sponsoring clinical trial NCT05081882?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05081882 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.