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NCT05079919 · ClinicalTrials.gov registry record · Phase 3
A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia
A Phase 3 study, sponsored by Ionis Pharmaceuticals.
- Completed
- Registry status
- Phase 3
- Development phase
- 617
- Enrollment target
NCT05079919: Completed Phase 3 study, sponsored by Ionis Pharmaceuticals.
NCT05079919 is a Phase 3 study that has completed, run by Ionis Pharmaceuticals. The registered enrollment target is 617 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05079919, a Phase 3 study, has completed, sponsored by Ionis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 617 participants
- Enrollment target
Study Summary
The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.
Interventions
- DRUG Placebo
- DRUG Olezarsen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 617 participants |
| Start Date | 2021-10-25 |
| Est. Completion | 2025-07-08 |
| Phase | Phase 3 |
What the finished NCT05079919 record still lists
NCT05079919 is an interventional study that assigns participants to a tested intervention. The registered 617 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05079919 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05079919 about?
NCT05079919 is a clinical study titled "A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia". The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from baseline.
What is the current status of trial NCT05079919?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 617 participants. The study started on 2021-10-25. Estimated completion is 2025-07-08.
What interventions are being tested in trial NCT05079919?
The interventions under investigation include: Placebo (DRUG), Olezarsen (DRUG).
Who is sponsoring clinical trial NCT05079919?
This trial is sponsored by Ionis Pharmaceuticals, which has 76 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05079919's enrollment target sits among peer trials
617 592nd of 2000 higher than 1,408 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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