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NCT05076708 · ClinicalTrials.gov registry record · Early Phase 1
The Effects of IQOS Use on Cigarette Smoking Behaviors
A Early Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 102
- Enrollment target
NCT05076708: Completed Early Phase 1 study, sponsored by University of Pennsylvania.
NCT05076708 is a Early Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 102 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05076708, a Early Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 102 participants
- Enrollment target
Study Summary
This within-subjects study aims to evaluate the effects of IQOS use on combustible cigarette smoking behaviors among 100 cigarette smokers who completed the study. After measuring baseline cigarette smoking rate, participants will receive an IQOS device and be instructed to use it (versus cigarettes) over a 14-day period. The investigators will also examine which objective and subjective effects of IQOS use predict a complete and incomplete switch from cigarettes to IQOS.
Primary Outcome
The primary outcome was the count of cigarettes per day (CPD) across the 14-day switch period (days 8-21) compared with the average CPD at baseline (days 1-5). This outcome was determined by counting each daily spent cigarette filter returned and self-reported CPD. The correlation between self-report and spent filter return was r=0.98. For the analysis, the daily counts were transformed to a percentage of the participant's average smoking rate from the baseline ad-lib smoking period.
Interventions
- OTHER IQOS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 102 participants |
| Start Date | 2021-08-26 |
| Est. Completion | 2024-05-31 |
| Phase | Early Phase 1 |
What the finished NCT05076708 record still lists
NCT05076708 is an interventional study that assigns participants to a tested intervention. The registered 102 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% higher).
The record links to 0 conditions, and to 1 intervention - of which IQOS is the first listed.
NCT05076708 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05076708 about?
NCT05076708 is a clinical study titled "The Effects of IQOS Use on Cigarette Smoking Behaviors". This within-subjects study aims to evaluate the effects of IQOS use on combustible cigarette smoking behaviors among 100 cigarette smokers who completed the study. After measuring baseline cigarette smoking rate, participants will receive an IQOS device and be instructed to use it (versus cigarettes...
What is the current status of trial NCT05076708?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 102 participants. The study started on 2021-08-26. Estimated completion is 2024-05-31.
What interventions are being tested in trial NCT05076708?
The interventions under investigation include: IQOS (OTHER).
Who is sponsoring clinical trial NCT05076708?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05076708's enrollment target sits among peer trials
102 181st of 2000 higher than 1,820 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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