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NCT05074498 · ClinicalTrials.gov registry record · Phase 1

Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TB006 in Participants With Alzheimer's Disease

A Phase 1 study, sponsored by TrueBinding.

Completed
Registry status
Phase 1
Development phase
154
Enrollment target

NCT05074498 is a Phase 1 study that has completed, run by TrueBinding. The registered enrollment target is 154 participants.

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The verdict

NCT05074498, a Phase 1 study, has completed, sponsored by TrueBinding.

COMPLETED
Registry status
Phase 1
Development phase
154 participants
Enrollment target

Study Summary

Part 1 of this study will be conducted to determine the safety, tolerability, and pharmacokinetic (PK) profile of multiple doses of TB006, as well as the maximum tolerated dose of TB006, and to assess the immunogenicity of TB006 (production of anti-TB006 antibody). Part 2 of this study will be conducted to determine the clinical efficacy of TB006 in participants with mild to severe Alzheimer's Disease.

Interventions

  • DRUG Placebo
  • DRUG TB006

Trial Details

FieldValue
Enrollment Target 154 participants
Start Date 2021-10-08
Est. Completion 2022-10-13
Phase Phase 1

Sponsor

TrueBinding

4 total trials

What the Registry Record Tells You About NCT05074498

The ClinicalTrials.gov registry entry for NCT05074498 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 154 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is TrueBinding, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05074498 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05074498 about?

NCT05074498 is a clinical study titled "Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TB006 in Participants With Alzheimer's Disease". Part 1 of this study will be conducted to determine the safety, tolerability, and pharmacokinetic (PK) profile of multiple doses of TB006, as well as the maximum tolerated dose of TB006, and to assess the immunogenicity of TB006 (production of anti-TB006 antibody). Part 2 of this study will be condu...

What is the current status of trial NCT05074498?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 154 participants. The study started on 2021-10-08. Estimated completion is 2022-10-13.

What interventions are being tested in trial NCT05074498?

The interventions under investigation include: Placebo (DRUG), TB006 (DRUG).

Who is sponsoring clinical trial NCT05074498?

This trial is sponsored by TrueBinding, which has 4 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.