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NCT05072587 · ClinicalTrials.gov registry record · NA
Dietary Oxysterols and β-Cell Function Among African Americans
A NA study, sponsored by Morehouse School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT05072587: Completed NA study, sponsored by Morehouse School of Medicine.
NCT05072587 is a NA study that has completed, run by Morehouse School of Medicine. The registered enrollment target is 12 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05072587, a NA study, has completed, sponsored by Morehouse School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
African Americans (AAs) have a higher risk of developing type 2 diabetes than the general population. AAs are also more likely to eat foods that contain cholesterol oxides/oxysterols. Dietary oxysterols can harm the cells that produce insulin and decrease insulin production. This pilot study seeks to determine if removing dietary oxysterols with a plant-based diet will improve insulin production and decrease the risk of type 2 diabetes among AAs.
Primary Outcome
The HOMA-B index will be calculated using the HOMA2 Calculator with fasting C-peptide and fasting blood glucose levels. This study will compare the effect of the standard American Diabetes Association (ADA) diet that contains oxysterols and a plant-based ADA diet that does not contain oxysterols on the HOMA-B index of African Americans (AAs) with prediabetes and early diabetes.
Interventions
- BEHAVIORAL Plant-based diet with no oxysterols
- BEHAVIORAL Standard ADA Diet (SADA)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2023-12-31 |
| Phase | NA |
What the finished NCT05072587 record still lists
NCT05072587 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Plant-based diet with no oxysterols is the first listed.
NCT05072587 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05072587 about?
NCT05072587 is a clinical study titled "Dietary Oxysterols and β-Cell Function Among African Americans". African Americans (AAs) have a higher risk of developing type 2 diabetes than the general population. AAs are also more likely to eat foods that contain cholesterol oxides/oxysterols. Dietary oxysterols can harm the cells that produce insulin and decrease insulin production. This pilot study seeks...
What is the current status of trial NCT05072587?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2021-07-01. Estimated completion is 2023-12-31.
What interventions are being tested in trial NCT05072587?
The interventions under investigation include: Plant-based diet with no oxysterols (BEHAVIORAL), Standard ADA Diet (SADA) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05072587?
This trial is sponsored by Morehouse School of Medicine, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05072587's enrollment target sits among peer trials
12 1913th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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