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NCT05067127 · ClinicalTrials.gov registry record · Phase 3

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

A Phase 3 study, sponsored by Apellis Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
124
Enrollment target

NCT05067127 is a Phase 3 study that has completed, run by Apellis Pharmaceuticals. The registered enrollment target is 124 participants.

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The verdict

NCT05067127, a Phase 3 study, has completed, sponsored by Apellis Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
124 participants
Enrollment target

Study Summary

This is a Phase 3 study to assess the efficacy and safety of twice-weekly subcutaneous (SC) doses of pegcetacoplan compared to placebo in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN) on the basis of a reduction in proteinuria.

Interventions

  • OTHER Placebo
  • DRUG Pegcetacoplan

Trial Details

FieldValue
Enrollment Target 124 participants
Start Date 2021-11-12
Est. Completion 2025-01-14
Phase Phase 3

Sponsor

Apellis Pharmaceuticals

21 total trials

What the Registry Record Tells You About NCT05067127

The ClinicalTrials.gov registry entry for NCT05067127 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 124 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Apellis Pharmaceuticals, which has 21 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05067127 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05067127 about?

NCT05067127 is a clinical study titled "Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis". This is a Phase 3 study to assess the efficacy and safety of twice-weekly subcutaneous (SC) doses of pegcetacoplan compared to placebo in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN) on the basis of a reduction in proteinuria.

What is the current status of trial NCT05067127?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 124 participants. The study started on 2021-11-12. Estimated completion is 2025-01-14.

What interventions are being tested in trial NCT05067127?

The interventions under investigation include: Placebo (OTHER), Pegcetacoplan (DRUG).

Who is sponsoring clinical trial NCT05067127?

This trial is sponsored by Apellis Pharmaceuticals, which has 21 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.