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NCT05065008 · ClinicalTrials.gov registry record · NA

The Roles of Gut Microbiome in UTI Susceptible Women

A NA study of Healthy, sponsored by University of Florida.

Active
Registry status
NA
Development phase
160
Enrollment target
1
Study location

NCT05065008: Active NA study of Healthy, sponsored by University of Florida.

NCT05065008 is a NA study of Healthy that is active but no longer recruiting, run by University of Florida. The registered enrollment target is 160 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05065008, a NA study of Healthy, is active but no longer recruiting, sponsored by University of Florida.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
160 participants
Enrollment target
1
Study location

Study Summary

Clinical trials on cranberry juice and UTI prevention yielded both positive and negative results for unknown reason. Gut microbiome in women affect the absorption and metabolism of cranberry bioactives. The variation of gut microbiome is a probable mechanism for metabolic polymorphisms and disparity in UTI prevention in women.

Primary Outcome

Compare the statistical differences between the changes from baseline in the an-adhesion activity against uropathogenic E. coli in UTI-susceptible women after consuming the cranberry juice for 3 weeks versus after consuming the placebo juice for 3 weeks. Anti-adhesion activity in urine will be measured using a fluorescence-based microplate method. The anti-adhesion activities of urines will be expressed by its equivalence to myricetin level. The unit for urine anti-adhesion activities is µg myri

Conditions Studied

Interventions

  • OTHER Cranberry juice
  • OTHER Apple juice

Study Locations (1)

Florida

  • University of Florida - Gainesville

Trial Details

FieldValue
Enrollment Target 160 participants
Start Date 2021-10-18
Est. Completion 2026-08
Phase NA
University of Florida

1,106 total trials

What the registry record for NCT05065008 still lists

NCT05065008 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (75% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Cranberry juice is the first listed.

NCT05065008 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT05065008 about?

NCT05065008 is a clinical study titled "The Roles of Gut Microbiome in UTI Susceptible Women". Clinical trials on cranberry juice and UTI prevention yielded both positive and negative results for unknown reason. Gut microbiome in women affect the absorption and metabolism of cranberry bioactives. The variation of gut microbiome is a probable mechanism for metabolic polymorphisms and disparity...

What is the current status of trial NCT05065008?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2021-10-18. Estimated completion is 2026-08.

What conditions does trial NCT05065008 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT05065008?

The interventions under investigation include: Cranberry juice (OTHER), Apple juice (OTHER).

Who is sponsoring clinical trial NCT05065008?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05065008 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05065008's enrollment target sits among peer trials

160 145th of 1090 higher than 944 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05065008, the US trial registry maintained by the National Library of Medicine. NCT05065008 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.