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COMPLETED Phase 2

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

NCT05057247 · View on ClinicalTrials.gov ↗

Study Summary

This trial that is investigating a medication called duvelisib in combination with docetaxel for the treatment of squamous cell carcinoma of the head and neck (SCCHN) that has returned or spread outside the head and neck area. The names of the study drugs involved in this study are: * Duvelisib (PI3K inhibitor) * Docetaxel chemotherapy

Interventions

  • DRUG Docetaxel
  • DRUG Duvelisib

Study Locations (1)

Massachusetts

  • Dana Farber Cancer Institute — Boston

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2021-10-14
Est. Completion 2024-06-13
Phase Phase 2

Sponsor

Glenn J. Hanna

62 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05057247

The ClinicalTrials.gov registry entry for NCT05057247 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Glenn J. Hanna, which has 62 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Advanced Head and Neck Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions — of which Docetaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05057247 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05057247 about?

NCT05057247 is a clinical study titled "Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC". This trial that is investigating a medication called duvelisib in combination with docetaxel for the treatment of squamous cell carcinoma of the head and neck (SCCHN) that has returned or spread outside the head and neck area. The names of the study drugs involved in this study are: * Duvelisib (P...

What is the current status of trial NCT05057247?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2021-10-14. Estimated completion is 2024-06-13.

What conditions does trial NCT05057247 study?

This clinical trial studies the following conditions: Advanced Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer, Squamous Cell Carcinoma of the Head and Neck (SCCHN), Recurrent Squamous Cell Carcinoma of the Head and Neck, Advanced Head and Neck Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05057247?

The interventions under investigation include: Docetaxel (DRUG), Duvelisib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05057247?

This trial is sponsored by Glenn J. Hanna, which has 62 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05057247 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial