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NCT05050097 · ClinicalTrials.gov registry record · Phase 1
A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
A Phase 1 study of Multiple Myeloma, sponsored by Janssen Research & Development.
- Active
- Registry status
- Phase 1
- Development phase
- 166
- Enrollment target
- 20
- Study locations
NCT05050097: Active Phase 1 study of Multiple Myeloma, sponsored by Janssen Research & Development.
NCT05050097 is a Phase 1 study of Multiple Myeloma that is active but no longer recruiting, run by Janssen Research & Development. The registered enrollment target is 166 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (70% lower). The trial reports 20 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05050097, a Phase 1 study of Multiple Myeloma, is active but no longer recruiting, sponsored by Janssen Research & Development.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 166 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to characterize the safety and tolerability of talquetamab when administered in different combination regimens and to identify the safe dose(s) of talquetamab combination regimens.
Primary Outcome
An AE is any untoward medical occurrence in a participant participating in a clinical study that does not necessarily have a causal relationship with the pharmaceutical/biological agent under study.
Conditions Studied
Interventions
- DRUG Lenalidomide
- DRUG Pomalidomide
- DRUG Carfilzomib
- DRUG Talquetamab
- DRUG Daratumumab SC
Study Locations (20)
Other
- St Vincents Hospital Melbourne - Fitzroy
- Alfred Health - Melbourne
- Gold Coast University Hospital - Southport
- Wollongong Hospital - Wollongong
- Cliniques Universitaires St-Luc - Brussels
- UZA - Edegem
- UZ Gent - Ghent
- UZ Leuven - Leuven
New York
- Mt. Sinai School of Medicine - New York
- Weill Cornell Medical College - New York
Alabama
- University of Alabama Birmingham - Birmingham
California
- University of California San Francisco - San Francisco
Colorado
- Colorado Blood Cancer Institute - Denver
Georgia
- Emory University - Atlanta
Indiana
- Indiana University - Indianapolis
New Jersey
- Hackensack University Medical Center - Hackensack
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 166 participants |
| Start Date | 2021-09-22 |
| Est. Completion | 2027-04-07 |
| Phase | Phase 1 |
What the registry record for NCT05050097 still lists
NCT05050097 is an interventional study that assigns participants to a tested intervention. The registered 166 participants enrollment target is mid-sized for trials with a published cap, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (70% lower).
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions - of which Lenalidomide is the first listed.
NCT05050097 names 20 study sites across 12 states, led by Other, New York, Alabama.
Frequently Asked Questions
What is clinical trial NCT05050097 about?
NCT05050097 is a clinical study titled "A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma". The purpose of this study is to characterize the safety and tolerability of talquetamab when administered in different combination regimens and to identify the safe dose(s) of talquetamab combination regimens.
What is the current status of trial NCT05050097?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 166 participants. The study started on 2021-09-22. Estimated completion is 2027-04-07.
What conditions does trial NCT05050097 study?
This clinical trial studies the following conditions: Multiple Myeloma.
What interventions are being tested in trial NCT05050097?
The interventions under investigation include: Lenalidomide (DRUG), Pomalidomide (DRUG), Carfilzomib (DRUG), Talquetamab (DRUG), Daratumumab SC (DRUG).
Who is sponsoring clinical trial NCT05050097?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05050097 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05050097's enrollment target sits among peer trials
166 125th of 438 higher than 314 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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