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NCT05049616 · ClinicalTrials.gov registry record · Phase 4
Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
A Phase 4 study, sponsored by The University of Texas Health Science Center, Houston.
- Completed
- Registry status
- Phase 4
- Development phase
- 70
- Enrollment target
NCT05049616: Completed Phase 4 study, sponsored by The University of Texas Health Science Center, Houston.
NCT05049616 is a Phase 4 study that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 70 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05049616, a Phase 4 study, has completed, sponsored by The University of Texas Health Science Center, Houston.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 70 participants
- Enrollment target
Study Summary
The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water pills, help rid your body of salt and water) will control blood pressure better than a different blood pressure medication of calcium channel blocker (lower your blood pressure by preventing calcium from entering the cells of your heart and arteries). Both medications are part of our usual care for high blood pressure after delivery.
Primary Outcome
Stage 2 hypertension at day 7-10 after delivery (defined as SBP ≥ 140 and/or DBP ≥ 90 mmHg) or admission to the hospital for blood pressure control prior to day 10. Primary outcome will be calculated as the average BP reading for day 7-10 after delivery.
Interventions
- DRUG NIFEdipine ER
- DRUG ACE Inhibitors and Diuretics
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2021-10-18 |
| Est. Completion | 2023-09-01 |
| Phase | Phase 4 |
What the finished NCT05049616 record still lists
NCT05049616 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which NIFEdipine ER is the first listed.
NCT05049616 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05049616 about?
NCT05049616 is a clinical study titled "Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension". The purpose of this study is to see if a combined pill of Angiotensin-converting enzyme (ACE) inhibitors (a medication that helps relax your veins and arteries to lower your blood pressure) with diuretics (sometimes called water pills, help rid your body of salt and water) will control blood pressur...
What is the current status of trial NCT05049616?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 70 participants. The study started on 2021-10-18. Estimated completion is 2023-09-01.
What interventions are being tested in trial NCT05049616?
The interventions under investigation include: NIFEdipine ER (DRUG), ACE Inhibitors and Diuretics (DRUG).
Who is sponsoring clinical trial NCT05049616?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05049616's enrollment target sits among peer trials
70 1043rd of 2000 higher than 931 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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