Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05048719 · ClinicalTrials.gov registry record · Phase 2

A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus

A Phase 2 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 2
Development phase
383
Enrollment target

NCT05048719: Completed Phase 2 study, sponsored by Eli Lilly and Company.

NCT05048719 is a Phase 2 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 383 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (188% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05048719, a Phase 2 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 2
Development phase
383 participants
Enrollment target

Study Summary

The main purpose of this study is to evaluate the efficacy and safety of LY3502970 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 30 weeks.

Primary Outcome

HbA1c is the glycosylated fraction of hemoglobin A. HbA1c is measured to identify average plasma glucose concentration over prolonged periods of time. Least Squares (LS) mean was determined by mixed model repeated measures (MMRM) model with Baseline + Country + Baseline HbA1c Group (\<=8.0%, \>8.0%) + Treatment + Time + Treatment\*Time (Type III sum of squares) as variables.

Interventions

  • DRUG Placebo
  • DRUG Dulaglutide
  • DRUG LY3502970

Trial Details

FieldValue
Enrollment Target 383 participants
Start Date 2021-09-15
Est. Completion 2022-09-30
Phase Phase 2
Eli Lilly and Company

1,341 total trials

What the finished NCT05048719 record still lists

NCT05048719 is an interventional study that assigns participants to a tested intervention. The registered 383 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (188% higher).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT05048719 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05048719 about?

NCT05048719 is a clinical study titled "A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus". The main purpose of this study is to evaluate the efficacy and safety of LY3502970 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 30 weeks.

What is the current status of trial NCT05048719?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 383 participants. The study started on 2021-09-15. Estimated completion is 2022-09-30.

What interventions are being tested in trial NCT05048719?

The interventions under investigation include: Placebo (DRUG), Dulaglutide (DRUG), LY3502970 (DRUG).

Who is sponsoring clinical trial NCT05048719?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05048719's enrollment target sits among peer trials

383 111th of 2000 higher than 1,890 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06056830 · 383 participants · Phase 3

    Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

  • NCT06277661 · 384 participants · NA

    The Mom and Infant Outcomes (MOMI) Study

  • NCT06372964 · 384 participants · Phase 3

    Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients

  • NCT06501040 · 384 participants · NA

    Increasing Knowledge and Interest in Cancer Clinical Trials

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05048719, the US trial registry maintained by the National Library of Medicine. NCT05048719 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.