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NCT05044845 · ClinicalTrials.gov registry record
Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy
A clinical trial of Hemophilia B and Gene Therapy, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- 150
- Enrollment target
- 6
- Study locations
NCT05044845 is a study of Hemophilia B and Gene Therapy that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 150 participants, above the 89-participant average among 20 other Hemophilia B trials with a reported enrollment target (69% higher). The trial reports 6 study locations across 2 states.
The verdict
NCT05044845, a study of Hemophilia B and Gene Therapy, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- 150 participants
- Enrollment target
- 6
- Study locations
Study Summary
Gene therapy is a paradigm-shifting treatment for hemophilia B patients, particularly in resource-limited countries where factor availability remains low. Transparent and culturally sensitive communication around gene therapy is vital to the success of a high-quality consenting process. Current literature on knowledge, beliefs and attitudes about gene therapy in resource-limited countries is inadequate. In addition, few educational resources to explain basic gene therapy concepts exist in languages other than English. This study aims to address these gaps in knowledge and aid for the development of educational resources to assist the informed consent processes for gene therapy in resource-limited countries. Primary Objective: To assess baseline knowledge, beliefs, and attitudes about gene therapy held by hemophilia B patients globally Secondary Objectives: 1. To explore healthcare workers' (i.e., physicians, nurses, social workers, educators/academic coordinators) perspectives regarding the education needs of hemophilia B patients globally 2. To explore healthcare workers beliefs and attitudes about gene therapy 3. To identify preferences of patients with hemophilia B and their healthcare workers on how/by what method or pathway educational content should be provided.
Conditions Studied
Interventions
- BEHAVIORAL Interview
Study Locations (6)
Other
- Civil Service Hospital - Kathmandu
- Hospital Dos De Mayo - Lima
- National Hospital of Sri Lanka - Colombo
- Ramathibodi Hospital - Bangkok
- National Institute of Hematology and Blood Transfusion - Hanoi
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2022-01-18 |
| Est. Completion | 2025-10-14 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05044845
The ClinicalTrials.gov registry entry for NCT05044845 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 89-participant average among 20 other Hemophilia B trials with a reported enrollment target (69% higher). The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hemophilia B appearing as the primary indexed condition, and to 1 intervention - of which Interview is the first listed.
NCT05044845 reports 6 study locations spanning 2 distinct geographic areas - top geographies include Other, Tennessee.
Frequently Asked Questions
What is clinical trial NCT05044845 about?
NCT05044845 is a clinical study titled "Needs Assessment of Knowledge, Beliefs, and Attitudes of Patients With Hemophilia B About Gene Therapy". Gene therapy is a paradigm-shifting treatment for hemophilia B patients, particularly in resource-limited countries where factor availability remains low. Transparent and culturally sensitive communication around gene therapy is vital to the success of a high-quality consenting process. Current lite...
What is the current status of trial NCT05044845?
This trial is currently completed. The enrollment target is 150 participants. The study started on 2022-01-18. Estimated completion is 2025-10-14.
What conditions does trial NCT05044845 study?
This clinical trial studies the following conditions: Hemophilia B, Gene Therapy.
What interventions are being tested in trial NCT05044845?
The interventions under investigation include: Interview (BEHAVIORAL).
Who is sponsoring clinical trial NCT05044845?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05044845 being conducted?
This trial has 6 study locations across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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