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NCT05043454 · ClinicalTrials.gov registry record · NA
Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults
A NA study, sponsored by University of Alabama at Birmingham.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT05043454: Completed NA study, sponsored by University of Alabama at Birmingham.
NCT05043454 is a NA study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 11 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05043454, a NA study, has completed, sponsored by University of Alabama at Birmingham.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
The investigator aims to assess the extent to which a brief exercise intervention improves systemic growth factor concentrations, reverses loss of systemic vascular networks and hypertension, and by extension, improves neurocognition. To test the investigator's hypothesis that increased cardiovascular fitness will correlate with improved vascular density, the investigator proposes the innovative use of retinal density scans.
Primary Outcome
This test will measure participants' maximal oxygen utilization and will be done once before and once after exercise intervention. The investigator will use a graded exercise test on a stationary cycle. The test will continue to maximum, and expired gases will be collected (via a spirometer) throughout the test to monitor oxygen consumption and carbon dioxide expiration. The investigator defines maximum or test termination as either voluntary exhaustion by the participant, or by two of three phy
Interventions
- OTHER High Intensity Interval Training (HIIT) Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2021-10-01 |
| Est. Completion | 2025-07-09 |
| Phase | NA |
What the finished NCT05043454 record still lists
NCT05043454 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which High Intensity Interval Training (HIIT) Exercise is the first listed.
NCT05043454 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05043454 about?
NCT05043454 is a clinical study titled "Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults". The investigator aims to assess the extent to which a brief exercise intervention improves systemic growth factor concentrations, reverses loss of systemic vascular networks and hypertension, and by extension, improves neurocognition. To test the investigator's hypothesis that increased cardiovascul...
What is the current status of trial NCT05043454?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2021-10-01. Estimated completion is 2025-07-09.
What interventions are being tested in trial NCT05043454?
The interventions under investigation include: High Intensity Interval Training (HIIT) Exercise (OTHER).
Who is sponsoring clinical trial NCT05043454?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05043454's enrollment target sits among peer trials
11 1927th of 2000 higher than 74 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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