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NCT05041712 · ClinicalTrials.gov registry record
Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation
A clinical trial of Children and Extracorporeal Membrane Oxygenation, sponsored by Johns Hopkins University.
- Completed
- Registry status
- 455
- Enrollment target
- 11
- Study locations
NCT05041712: Completed study of Children and Extracorporeal Membrane Oxygenation, sponsored by Johns Hopkins University.
NCT05041712 is a study of Children and Extracorporeal Membrane Oxygenation that has completed, run by Johns Hopkins University. The registered enrollment target is 455 participants, below the 357,264-participant average among 14 other Children trials with a reported enrollment target (100% lower). The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05041712, a study of Children and Extracorporeal Membrane Oxygenation, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- 455 participants
- Enrollment target
- 11
- Study locations
Study Summary
The BEAM study is a multicenter, prospective, observational study in children supported on extracorporeal membrane oxygenation (ECMO). The primary goals of this study are to develop and refine a brain injury multimarker panel for accurate neurologic monitoring at the bedside and early classification of mortality and disability outcomes of critically ill children supported on ECMO.
Primary Outcome
VABS-3 is a 381-item caregiver report measure that was developed to assess adaptive behavior. The questionnaire is divided into 4 domains of adaptive behavior: 1) communication, 2) daily living, 3) social skills and relationships, and 4) physical activity. Each item is rated 0 (never), 1 (sometimes), or 2 (usually or often) as how often the child does the behavior independently without help or reminders. The overall adaptive composite score has a mean of 100 and standard deviation of 15 with low
Conditions Studied
Study Locations (11)
California
- Children's Hospital Los Angeles - Los Angeles
- University of California Los Angeles - Los Angeles
District of Columbia
- Children's National Medical Center - Washington D.C.
Indiana
- Riley Hospital for Children - Indianapolis
Maryland
- Johns Hopkins University - Baltimore
Massachusetts
- Boston Children's Hospital - Boston
Missouri
- St. Louis Children's Hospital - St Louis
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Tennessee
- University of Tennessee Health Science Center - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 455 participants |
| Start Date | 2019-12-06 |
| Est. Completion | 2025-05-05 |
What the finished NCT05041712 record still lists
NCT05041712 is an observational study that tracks outcomes without assigning an intervention. The registered 455 participants enrollment target is mid-sized for trials with a published cap, below the 357,264-participant average among 14 other Children trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Children appearing as the primary indexed condition, and to 0 interventions.
NCT05041712 lists 11 locations in 10 states (California, District of Columbia, Indiana).
Frequently Asked Questions
What is clinical trial NCT05041712 about?
NCT05041712 is a clinical study titled "Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation". The BEAM study is a multicenter, prospective, observational study in children supported on extracorporeal membrane oxygenation (ECMO). The primary goals of this study are to develop and refine a brain injury multimarker panel for accurate neurologic monitoring at the bedside and early classification...
What is the current status of trial NCT05041712?
This trial is currently completed. The enrollment target is 455 participants. The study started on 2019-12-06. Estimated completion is 2025-05-05.
What conditions does trial NCT05041712 study?
This clinical trial studies the following conditions: Children, Extracorporeal Membrane Oxygenation, Neurologic Injury.
Who is sponsoring clinical trial NCT05041712?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05041712 being conducted?
This trial has 11 study locations across California, District of Columbia, Indiana, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05041712's enrollment target sits among peer trials
455 2nd of 14 the highest of 14 other Children trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Children trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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