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Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation
NCT05041712 · View on ClinicalTrials.gov ↗
Study Summary
The BEAM study is a multicenter, prospective, observational study in children supported on extracorporeal membrane oxygenation (ECMO). The primary goals of this study are to develop and refine a brain injury multimarker panel for accurate neurologic monitoring at the bedside and early classification of mortality and disability outcomes of critically ill children supported on ECMO.
Conditions Studied
Study Locations (11)
California
- Children's Hospital Los Angeles — Los Angeles
- University of California Los Angeles — Los Angeles
District of Columbia
- Children's National Medical Center — Washington D.C.
Indiana
- Riley Hospital for Children — Indianapolis
Maryland
- Johns Hopkins University — Baltimore
Massachusetts
- Boston Children's Hospital — Boston
Missouri
- St. Louis Children's Hospital — St Louis
Pennsylvania
- Children's Hospital of Philadelphia — Philadelphia
Tennessee
- University of Tennessee Health Science Center — Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 455 participants |
| Start Date | 2019-12-06 |
| Est. Completion | 2025-05-05 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05041712
The ClinicalTrials.gov registry entry for NCT05041712 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 455 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,517 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Children appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05041712 reports 11 study locations spanning 10 distinct geographic areas — top geographies include California, District of Columbia, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05041712 about?
NCT05041712 is a clinical study titled "Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation". The BEAM study is a multicenter, prospective, observational study in children supported on extracorporeal membrane oxygenation (ECMO). The primary goals of this study are to develop and refine a brain injury multimarker panel for accurate neurologic monitoring at the bedside and early classification...
What is the current status of trial NCT05041712?
This trial is currently completed. The enrollment target is 455 participants. The study started on 2019-12-06. Estimated completion is 2025-05-05.
What conditions does trial NCT05041712 study?
This clinical trial studies the following conditions: Children, Extracorporeal Membrane Oxygenation, Neurologic Injury. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05041712?
This trial is sponsored by Johns Hopkins University, which has 1,517 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05041712 being conducted?
This trial has 11 study locations across California, District of Columbia, Indiana, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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