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NCT05040087 · ClinicalTrials.gov registry record · NA
Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)
A NA study of Type 2 Diabetes, sponsored by Foundation for Atlanta Veterans Education and Research.
- Active
- Registry status
- NA
- Development phase
- 127
- Enrollment target
- 1
- Study location
NCT05040087: Active NA study of Type 2 Diabetes, sponsored by Foundation for Atlanta Veterans Education and Research.
NCT05040087 is a NA study of Type 2 Diabetes that is active but no longer recruiting, run by Foundation for Atlanta Veterans Education and Research. The registered enrollment target is 127 participants, below the 3,923-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05040087, a NA study of Type 2 Diabetes, is active but no longer recruiting, sponsored by Foundation for Atlanta Veterans Education and Research.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 127 participants
- Enrollment target
- 1
- Study location
Study Summary
Diabetes is a disorder of high blood glucose, that tends to get worse; over time, patients need more and more drugs. This pattern is caused by overwork of the body's insulin-producing β-cells, because patients' glucose levels are typically above normal; if the investigators kept glucose levels normal - reducing β-cell work - the investigators might be able to keep the disease from getting worse. This trial is aimed to show that adjusting the drugs to keep glucose levels normal, can help to preserve β-cell function compared to usual diabetes care, possibly reduce the tendency to develop the eye and kidney complications of diabetes, and might also be more cost-effective than usual care.
Primary Outcome
HbA1c DIFFERENCEs, INTENSIVE Rx vs. CONTROLS - PRIMARY OUTCOME #1
Conditions Studied
Interventions
- OTHER Intensification of diabetes medication based largely on HbA1c levels
- OTHER Intensification of diabetes medication based on glucose levels
Study Locations (1)
Georgia
- Atlanta VA Medical Center - Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 127 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2027-03-31 |
| Phase | NA |
What the registry record for NCT05040087 still lists
NCT05040087 is an interventional study that assigns participants to a tested intervention. The registered 127 participants enrollment target is mid-sized for trials with a published cap, below the 3,923-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Type 2 Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Intensification of diabetes medication based largely on HbA1c levels is the first listed.
NCT05040087 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT05040087 about?
NCT05040087 is a clinical study titled "Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)". Diabetes is a disorder of high blood glucose, that tends to get worse; over time, patients need more and more drugs. This pattern is caused by overwork of the body's insulin-producing β-cells, because patients' glucose levels are typically above normal; if the investigators kept glucose levels norma...
What is the current status of trial NCT05040087?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 127 participants. The study started on 2021-09-01. Estimated completion is 2027-03-31.
What conditions does trial NCT05040087 study?
This clinical trial studies the following conditions: Type 2 Diabetes.
What interventions are being tested in trial NCT05040087?
The interventions under investigation include: Intensification of diabetes medication based largely on HbA1c levels (OTHER), Intensification of diabetes medication based on glucose levels (OTHER).
Who is sponsoring clinical trial NCT05040087?
This trial is sponsored by Foundation for Atlanta Veterans Education and Research, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05040087 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Type 2 Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05040087's enrollment target sits among peer trials
127 129th of 327 higher than 199 of 327 other Type 2 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 2 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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