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NCT07325747 · ClinicalTrials.gov registry record · NA
Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.
A NA study of Peri Implantitis, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07325747: Recruiting NA study of Peri Implantitis, sponsored by University of Michigan.
NCT07325747 is a NA study of Peri Implantitis that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 40 participants, below the 110-participant average among 4 other Peri Implantitis trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07325747, a NA study of Peri Implantitis, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test the comparative efficacy of two surgical approaches (immediate versus delayed GBR) for the surgical reconstruction of peri-implantitis intra-bony defects in terms of the clinical, radiographical, histological, volumetric, microbiological, and patient-reported outcomes. The investigators hypothesize that in certain clinical situations, treatment of peri-implantitis intra-bony defects with the use of a compound bone grafting material (mixture of allogenic bone substitutes) and a non-resorbable barrier membrane and following a delayed approach (test group) with initial phase of defect decontamination and initial healing phase would yield superior outcomes to that of the conventional approach (control group) of defect decontamination and regeneration at the same clinical visit while also significantly enhancing patient-reported outcomes: H0: There is no difference between the two mentioned approaches in terms of the treatment outcomes. H1: There is a significant difference, favoring the delayed approach compared to the immediate reconstruction.
Primary Outcome
change in radiographic bone volume will be measured
Conditions Studied
Interventions
- PROCEDURE Staged peri-implant debridement and regeneration
- PROCEDURE Simultaneous peri-implant debridement and regeneration
Study Locations (1)
Michigan
- University of Michigan School of Dentistry - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-01-12 |
| Est. Completion | 2028-12 |
| Phase | NA |
What NCT07325747 shows while recruiting
NCT07325747 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 110-participant average among 4 other Peri Implantitis trials with a reported enrollment target (64% lower).
The record links to 1 condition, with Peri Implantitis appearing as the primary indexed condition, and to 2 interventions - of which Staged peri-implant debridement and regeneration is the first listed.
NCT07325747 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT07325747 about?
NCT07325747 is a clinical study titled "Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.". The purpose of this study is to test the comparative efficacy of two surgical approaches (immediate versus delayed GBR) for the surgical reconstruction of peri-implantitis intra-bony defects in terms of the clinical, radiographical, histological, volumetric, microbiological, and patient-reported out...
What is the current status of trial NCT07325747?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-01-12. Estimated completion is 2028-12.
What conditions does trial NCT07325747 study?
This clinical trial studies the following conditions: Peri Implantitis.
What interventions are being tested in trial NCT07325747?
The interventions under investigation include: Staged peri-implant debridement and regeneration (PROCEDURE), Simultaneous peri-implant debridement and regeneration (PROCEDURE).
Who is sponsoring clinical trial NCT07325747?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07325747 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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