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NCT05020184 · ClinicalTrials.gov registry record · Phase 2
Effect of Oral Cimetidine in the Protoporphyrias
A Phase 2 study of Erythropoietic Protoporphyria and X-linked Protoporphyria, sponsored by Amy K. Dickey, M.D..
- Completed
- Registry status
- Phase 2
- Development phase
- 26
- Enrollment target
- 3
- Study locations
NCT05020184 is a Phase 2 study of Erythropoietic Protoporphyria and X-linked Protoporphyria that has completed, run by Amy K. Dickey, M.D.. The registered enrollment target is 26 participants. The trial reports 3 study locations across 3 states.
The verdict
NCT05020184, a Phase 2 study of Erythropoietic Protoporphyria and X-linked Protoporphyria, has completed, sponsored by Amy K. Dickey, M.D..
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 26 participants
- Enrollment target
- 3
- Study locations
Study Summary
Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) result from genetic defects of heme biosynthesis that cause life-long, painful cutaneous sensitivity to light. The objective of this study is to determine the efficacy and safety of oral cimetidine administration for treatment of the protoporphyrias. Efficacy will be based on protoporphyrin levels, photosensitivity, and quality of life questionnaires. Funding Source- FDA OOPD
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Cimetidine
Study Locations (3)
Massachusetts
- Massachusetts General Hospital - Boston
North Carolina
- Atrium Health Wake Forest Baptist Medical Center - Winston-Salem
Texas
- University of Texas Medical Branch - Galveston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2022-06-14 |
| Est. Completion | 2025-04-24 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05020184
The ClinicalTrials.gov registry entry for NCT05020184 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amy K. Dickey, M.D., which has 1 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Erythropoietic Protoporphyria appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05020184 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Massachusetts, North Carolina, Texas.
Frequently Asked Questions
What is clinical trial NCT05020184 about?
NCT05020184 is a clinical study titled "Effect of Oral Cimetidine in the Protoporphyrias". Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) result from genetic defects of heme biosynthesis that cause life-long, painful cutaneous sensitivity to light. The objective of this study is to determine the efficacy and safety of oral cimetidine administration for treatment of ...
What is the current status of trial NCT05020184?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2022-06-14. Estimated completion is 2025-04-24.
What conditions does trial NCT05020184 study?
This clinical trial studies the following conditions: Erythropoietic Protoporphyria, X-linked Protoporphyria.
What interventions are being tested in trial NCT05020184?
The interventions under investigation include: Placebo (DRUG), Cimetidine (DRUG).
Who is sponsoring clinical trial NCT05020184?
This trial is sponsored by Amy K. Dickey, M.D., which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05020184 being conducted?
This trial has 3 study locations across Massachusetts, North Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Erythropoietic Protoporphyria
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