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NCT05017831 · ClinicalTrials.gov registry record · NA

Shifting Perspectives R33 Phase: Enhancing Outcomes in Anorexia Nervosa With CRT

A NA study, sponsored by Children's Hospital of Philadelphia.

Completed
Registry status
NA
Development phase
283
Enrollment target

NCT05017831: Completed NA study, sponsored by Children's Hospital of Philadelphia.

NCT05017831 is a NA study that has completed, run by Children's Hospital of Philadelphia. The registered enrollment target is 283 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05017831, a NA study, has completed, sponsored by Children's Hospital of Philadelphia.

COMPLETED
Registry status
NA
Development phase
283 participants
Enrollment target

Study Summary

Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life. Research on executive functioning in anorexia nervosa indicates that it may be a viable target for intervention that could improve outcome. The current project focuses on determining whether or not the investigators can improve set-shifting in affected adolescents in the hopes that improvements in set-shifting will, ultimately, improve outcome.

Primary Outcome

Investigators will use the Delis Kaplan Executive Functioning System (D-KEFS ) Trails Number-Letter Sequencing subtest, a neurocognitive behavioral task, to assess ability to set-shift (a core component of executive functioning). Investigators will compare change in scaled scores from pre, during, and post-treatment across groups. Scaled scores range from 0-19 with higher scores indicating better executive functioning.

Interventions

  • BEHAVIORAL Cognitive Remediation Therapy
  • BEHAVIORAL Family Based Treatment

Trial Details

FieldValue
Enrollment Target 283 participants
Start Date 2021-11-05
Est. Completion 2025-05-21
Phase NA
Children's Hospital of Philadelphia

431 total trials

What the finished NCT05017831 record still lists

NCT05017831 is an interventional study that assigns participants to a tested intervention. The registered 283 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 2 interventions - of which Cognitive Remediation Therapy is the first listed.

NCT05017831 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05017831 about?

NCT05017831 is a clinical study titled "Shifting Perspectives R33 Phase: Enhancing Outcomes in Anorexia Nervosa With CRT". Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life. Research on executive functioning in anorexia nervosa indicates that it may be a via...

What is the current status of trial NCT05017831?

This trial is currently completed. It is a NA study. The enrollment target is 283 participants. The study started on 2021-11-05. Estimated completion is 2025-05-21.

What interventions are being tested in trial NCT05017831?

The interventions under investigation include: Cognitive Remediation Therapy (BEHAVIORAL), Family Based Treatment (BEHAVIORAL).

Who is sponsoring clinical trial NCT05017831?

This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05017831's enrollment target sits among peer trials

283 378th of 2000 higher than 1,622 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05017831, the US trial registry maintained by the National Library of Medicine. NCT05017831 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.