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NCT05016414 · ClinicalTrials.gov registry record · NA
Countermeasures for Visual Impairment in Astronauts
A NA study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT05016414: Completed NA study, sponsored by University of Texas Southwestern Medical Center.
NCT05016414 is a NA study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05016414, a NA study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
This study is being done to prevent changes in the vision of astronauts during prolonged residence on the International Space Station or a mission to Mars. This project will provide data about the efficacy of lower body negative pressure to mimic daily upright posture by intermittently lowering central venous pressure while in simulated microgravity (3 days of bed rest). The investigators expect that 3 days of bed rest will increase choroid thickness, and choroid area. The investigators hypothesize that nightly LBNP (-20mmHg) will prevent these changes.
Primary Outcome
The change in choroid area measured by optical coherence tomography.
Interventions
- OTHER Lower body negative pressure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2019-03-01 |
| Est. Completion | 2020-03-01 |
| Phase | NA |
What the finished NCT05016414 record still lists
NCT05016414 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Lower body negative pressure is the first listed.
NCT05016414 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05016414 about?
NCT05016414 is a clinical study titled "Countermeasures for Visual Impairment in Astronauts". This study is being done to prevent changes in the vision of astronauts during prolonged residence on the International Space Station or a mission to Mars. This project will provide data about the efficacy of lower body negative pressure to mimic daily upright posture by intermittently lowering cent...
What is the current status of trial NCT05016414?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2019-03-01. Estimated completion is 2020-03-01.
What interventions are being tested in trial NCT05016414?
The interventions under investigation include: Lower body negative pressure (OTHER).
Who is sponsoring clinical trial NCT05016414?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05016414's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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